Transcript Gluten Sensor

45
Beginning of the chapter
Gluten intolerance and Genetics
(Gluten Sensor)
SENSORS
GLUTEN SENSOR
Celiac disease / Gluten Intolerance
SENSORS
GLUTEN SENSOR
Gluten (Wheat protein)
Incorrect programming of the immune system (it fights
against gluten)
digestive problems
lactose intolerance
9x higher ENT tumor risk
80x higher lymphatic tumor risk
On average, 11 years until diagnosis
12% of the untreated cases are fatal
Gluten-free diet
>>>Complete freedom from symptoms
>>>Normalization of the other (tumor) risks
GLUTEN INTOLERANCE
Receptors and infections
ALARM!!!
The receptor is
built and the
bacterial proteins
are integrated
T-cell
The receptor presents
bacterial proteins
Bacteria
The bacteria is
broken up
Bacteria is
absorbed
DQ-A1
Receptor genes
DQ-B1
APC-cell
GLUTEN INTOLERANCE
Receptors and infections
Everything OK!
The receptor
cannot integrate
gluten
T-cell
Proteins are
broken up
Wheat protein
(gluten) is
absorbed
DQ-A1
Receptor gene
DQ-B1
APC-cell
GLUTEN INTOLERANCE
Receptors and infections
ALARM!!!
Gluten is
integrated into
the receptor
T-cell
The receptor contains Gluten
Proteins are
broken up
Wheat protein
(gluten) is
absorbed
DQ-A1
Receptor gene
DQ-B1
APC-cell
GLUTEN INTOLERANCE
Receptors and infections
What can we find out from the genetic analysis?
Negative -> The probability of gluten intolerance = ~0%
Positive -> The probability of gluten intolerance = up to 40%
Pay attention to symptoms > immediate, correct diagnosis
Gluten Free Diet > absolute freedom from symptoms
GLUTEN INTOLERANCE
Counselling example
EARLY DETECTION
1) Pay attention to the symptoms when eating gluten containing
products
DIETARY ADJUSTMENTS
1) Avoid gluten containing food
Nutrition Sensor can help
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End of the chapter
Gluten intolerance and genetics
(Gluten Sensor)