Transcript Immune Lines of Defence

Immune Lines of Defence
Skin - Video
• http://www.nature.com/ni/multimedia/skin/index.html
Skin- Video Quiz
1. What is the primary barrier against
pathogens?
a)
b)
c)
d)
Stomach acid
Mucous
Skin
Saliva
Skin- Video Quiz
2. What 3 layers compose the skin?
a)
b)
c)
d)
Epidermis, dermis, subcutaneous fat
Dermis, Keratinocytes, Corneocytes
Dendritic cells, collagen, elastin
Ectodermis, Dermis, Endodermis
Skin- Video Quiz
3. What do the “commensal bacteria” on the
surface of the skin do?
a)
b)
c)
d)
Cause inflammation
Protect against pathogens
Attack our skin cells
Nothing
Skin- Video Quiz
4. Corneocytes are the outermost skin cells.
Which adjective best describes them?
a)
b)
c)
d)
Living
Rapidly reproducing
Dead
Non-living
Skin- Video Quiz
5. What 2 types of materials make up the
“extracellular matrix” of the skin?
a)
b)
c)
d)
Fibrin and fibrogen
Coagulate and fibroblast
Elastin and collagen
Cellulose and chitin
Skin- Video Quiz
6. What kind of immune cell has more than
twice the number of individuals present
in skin than in blood?
a)
b)
c)
d)
T-cells
B-cells
Macrophages
Neutrophils
Skin- Video Quiz
7. Where do the activated Dendritic cells
go?
a)
b)
c)
d)
Blood stream
Body Tissue
Surface of the skin
Lymph nodes
Skin- Video Quiz
8. Why do “T-cells” kill infected
keratinocytes?
a)
b)
c)
d)
They reproduce too rapidly
They are cells from outside the body
To kill the virus they contain
To prevent them from destroying T-cells
Skin- Video Quiz
9. Why do “memory cells” remain in the
skin?
a)
b)
c)
d)
Quickly respond to future attacks
Block holes in the skin
Help with the healing process
Destroy commensal bacteria