Transcript TPJ_4816_sm_FigS1

(a)
Same-direction response in cat2 and in response to pathogen challenge
Induced in cat2 and by bacteria
avr
vir
11
36
Repressed in cat2 and by bacteria
avr
6
vir
1
1
Total in common
(11+36+6+1+1) / (64+6)
0
= 55/70
64 metabolites
induced in cat2
6 metabolites
decreased in cat2
Total in opposition
5
5
4
avr
0
vir
Induced in cat2, repressed by bacteria
3
1
avr
(5+5+4+3+1 ) / (64+6)
vir
= 18/70
Repressed in cat2, induced by bacteria
Opposite-direction response in cat2 and in response to pathogen challenge
Number of induced metabolites
80
(c)
avirulent
60
total
40
overlapping
with cat2
20
0
0
80
6
12
18
24
virulent
total
60
overlapping
with cat2
40
20
0
0
12
24
36
48
Number of induced metabolites
overlapping with cat2
(b)
64
48
66%
56%
32
61%
52%
39%
16
0
6h
12h
24h
avirulent
24h
48h
virulent
hpi
Supporting Information Figure S1. Overlap between cat2-associated metabolite profiles and those linked to avirulent or virulent
interactions.
70 metabolite derivatives were significantly changed in cat2 relative to Col-0: 64 were induced, while 6 were decreased relative to
Col-0 (see Table S1). (a) Overlap or antagonism between metabolite profiles in cat2 and in response to avirulent or virulent bacteria
(Table S1D). Pink outer frame, induced in cat2. Green outer frame, repressed in cat2. The numbers in the Venn diagram circles
refer to those metabolites that were significantly changed in cat2 that were also changed by bacterial challenge . Left (in outer pink
frame), number of metabolites induced in cat2 that were also significantly changed by bacterial challenge, either in the same (top) or
opposite (bottom) directions. Right (outer green frame), number of metabolites decreased in cat2 that were also significantly
changed by bacterial challenge, either in the same (top) or opposite (bottom) directions. (b) Time-specific changes in induced
metabolites (Table S1B). Circles, total number of significantly induced metabolites. Triangles, number of these metabolites that were
also induced in cat2 relative to Col-0. hpi, hours post inoculation. (c) Number and percentage of the 64 significantly induced
metabolites in cat2 that were also induced by avirulent or virulent bacterial challenge. Data are shown for all time points.