Transcript Lectures 12, 13 and 14 slides - Rob Phillips Group

APh161 - Lecture 11: The Cytoskeleton is
Always Under Construction
Mullins et al.
Rob Phillips
California Institute of Technology
The Hierarchy of Time Scales
Time Dependence of Gene Expression
Collins et al.
Elowitz et al.
Rate Equations and Genetic Circuits
The Rate Equation World View
Wong, Gladney, and Keasling ‘03
Vilar and Leibler ‘03
Putting the Stopwatch on Cell
Motility
http://cmgm.stanford.edu/theriot/movies.htm - the place to be!
Courtesy of Julie Theriot et al., Stanford
The Eukaryotic Cell Cycle
Adapted from Pollard and Earnshaw
Cytoskeletal Action During Cell Division
Cytoskeleton Mediated Mitosis
Show the movies in the Lecture 11 directory – see
http://www.bio.unc.edu/faculty/salmon/lab/mitosis/mitosismovies.html
Cell Division in Bacteria
Petra Levin
FtsZ rings during division
Polymerization Processes 1: Tobacco
Mosaic Virus
Caspar
Dynamics of Molecular Motors
Science, Vol 300, Issue 5628, 2061-2065, 27 June 2003 - Yildiz et al.
Rate Equations: Decay Processes
Rate Equations: Sum Over Trajectories
Rate Equations: Birthing Reactions
A reminder on the cytoskeleton
Actin, Microtubules, Intermediate
Filaments
Actin Polymerization Rate in vitro
ParM Length Distribution
Mullins et al., Science 2004
Actin and its Partners
Microtubule Dynamics: Part of the
Polymerization Puzzle
Microtubule Dynamics In Vitro
Show Borisy movies,
http://www.borisylab.nwu.edu/pages/supplemental/treadmill.html
Life at the Leading Edge
The Story of ParM
(Dyche Mullins et al.)