Transcript Actinomyces

Chapter 24
Actinomyces and Nocardia
教学大纲
掌握：放线菌属的形态染色、硫磺
样颗粒。
 熟悉：放线菌的致病性、与龋齿和
牙周炎关系。

Actinomyces




A. israeli,
A. naeslundii;
G＋
Anaerobic, form filament,
Exhibit true branching
Related to decay tooth and
peridentitis
Clinical specimens : Actinomycosis-pus
Sulfur granule is visible
Sections or
tabletting :
chrysanthemum-like
appearance
Opportunist organism, component of
oral flora (endogenous)
Take advantage of injury to penetrate
mucosal barriers
Trauma
 Surgery

Actinomycosis

A chronic suppurative and
granulomatous disease of the cervicofacial, thoracic or abdominal areas
Pus contains "Sulfur Granules"
yellow – orange
 Composed of mineralized “mycelial” mass
 Colony of bacteria

Form burrowing sinus tracts to skin or
mucus membranes——
Discharge purulent material
sulfur granule
Pulmonary
Actinomycosis
nocardia



Nocardiosis
G+, rod ，weakly acid-fast
N. asteroides; N. brasiliensis
Subcutaneous infections, pulmonary
infections, and brain abscesses
Subcutaneous infections
pulmonary infections
Mycetoma
(足分枝菌病）
Features of actinomycetes
Actinomyces: branching bacilli,
non-acid fastness, anaerobic,
oral ,intestinal ,endogenous flora,
chronic cellulitis, draining sinuses
Nocardia: branching bacilli ,weak acid
fast, aerobic, soil (exogenous ) ,
pseumonia ,skin pustules ,
brain abscess
summary


Actinomyces :stain ,clinical
feature, disease
Nocardia: stain, disease