Transcript Rectal Cancer: Three-year Review From a Pilot

Rectal Cancer: Three-year Review From a Pilot Screening Centre
Leung E., Francombe J., Tripuraneni G., Osborne M.
Department of Colorectal Surgery, Warwick Hospital, Lakin Road, Warwick, CV34 5BW, United Kingdom
Dukes’ staging
INTRODUCTION
Colorectal Cancer screening has been
demonstrated a significant reduction
in emergency cancer operations.
73 patients
Leung et al. The effects of population-based faecal occult
blood test screening upon emergency colorectal cancer
admissions in Coventry and north Warwickshire. Gut
2008;57:218–222.
No surgery
It remains unclear if there is a downregulation in histological staging,
recurrence or mortality rate.
This study intends to analyse these
parameters in rectal cancer patients
within the pilot screening programme.
METHODS
•Data on all rectal cancer patients
•Prospectively collected
•Between May 2001 and 2004
15%
Dukes’ A
Dukes’ B
Dukes’ C
Dukes’ D
19%
22%
33%
11%
Recurrence within 3 years
Mortality with 3 years
•19 patients (26%)
•7 patients (9.6%)
Lymphovascular invasion
Parameters reviewed:
Dukes’ and histological staging
Mortality and Recurrence
•47 patients (60%)
3 year follow-up
CONCLUSIONS
RESULTS
Rectal cancer in our pilot study has a 3 year mortality and recurrence rate
comparable with the UK national average.
•73 rectal cancer patients
- 39 men and 34 women
- Median age = 72
There is no evidence of improved staging during the pilot screening
programme.
•54 patients (73.9%) required adjuvant
therapy
Long term study is warranted to assess if screening can shift Dukes’
staging to the left, reduce recurrence and mortality rate from rectal cancer.