Transcript 8533056_cryosurgery

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Cryosurgery
Mohadese hashemi
Dr. Razjouyan
2008
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Introduction
Cryosurgery is a technique for
freezing and killing abnormal cells.
• is used to treat some kinds of cancer and
some precancerous or noncancerous
conditions
• can be used both inside the body and on the
skin.
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What is cryosurgery?
Cryosurgery (also called cryotherapy or
cryoablation ) is the use of extreme cold
produced by liquid nitrogen (or argon
gas) to destroy abnormal tissue.
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Brief history
The first cryogens were liquid air and
compressed carbon dioxide snow. Liquid
nitrogen became available in the 1940s
and currently is the most widely used
cryogen.
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Brief history
this method is being supplanted by liquid
nitrogen spray techniques is easy to use,
and similar techniques can be employed
to manage benign, premalignant, and
malignant lesions.
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Mechanism of Action
liquid nitrogen or argon gas is circulated
through a hollow instrument.
The doctor uses ultrasound or MRI to guide
the cryoprobe.
A ball of ice crystals forms around the probe,
freezing nearby cells.
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‫‪GENERAL ADVANTAGE OF CRYOSURGERY‬‬
‫• كاهش ميزان خون ريزي‬
‫• تنظيم ميزان بافت نابود شده‬
‫• كاهش درد‬
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Cryosurgery is an alternative to
SUEGERY for :
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Breast
Prostate
Early-stage skin cancers
Precancerous conditions of the cervix
liver cancer
Colon
Retinoblastoma
tumors of the bone
Parkinson
‫ترميم سبكيه ي جدا شده و ترميم آب مرواريد‬
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‫پاركينسون‬
‫از اولين كاربرد هاي جراحي با‬
‫سرما‬
‫توقف لرزش با استفاده از انهدام‬
‫بخشي از تاالموس‬
‫براي اولين بار در دهه ي ‪60‬‬
‫ميالدي توسط اروين كوپلر‬
‫انجام شد‬
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prostate cancer
can be used to treat men who have earlystage prostate cancer that is confined to
the prostate gland.
Long-term outcomes are not known
is not used to treat prostate cancer that has
spread outside the gland
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prostate cancer
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side effects
These side effects may occur more often in
men who have had radiation to the
prostate :
• lack of control over urine flow
• Many men become important
• In some cases, the surgery has caused
injury to the rectum
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primary liver cancer
The tumor and a half inch margin of
normal liver are frozen to -190°C for 15
minutes, which is lethal to all tissues.
The area is thawed for 10 minutes and
then re-frozen to -190°C for another 15
minutes.
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Side effect
Cryosurgery in the liver may cause damage
to the bile ducts and/or major blood
veseels, which can lead to hemorrhage
(heavy bleeding) or infection.
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skin cancer
Cryosurgery has been used to treat skin lesions
for approximately 100 years.
Benign skin lesions that are suitable for
freezing include actinic keratosis, solar
lentigo, seborrheic keratosis, viral wart,
molluscum contagiosum, and
Dermatofibroma.
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Advantages
• Cryosurgery requires little time and fits easily
into the physician's office schedule
• low risk of infection
• Short recovery times
• Minimal wound care suture removal
• cryosurgery requires no expensive supplies or
injectable anesthesia.
• treat AIDS-related Kaposi’s sarcoma when the
skin lesions are small and localized
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Disadvantage
• Scarring
• loss of sensation
• loss of pigmentation
• loss of hair in the treated area
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New advantages
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Simple pencil type grip for
easy use .
Very accurate application .
Freezes to -89ºC and to a depth of 3mm .
Interchangeable ‘contact’ heads for special
applications including GUM, Podiatry &
Dermatology .
• Avoids all of the storage and transport
problems associated with traditional
cryotherapy
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New advantages
• Once a cylinder has been
attached CryoAlfa can be kept
in a drawer without degradation of the N20
contents for approximately 3 months .
• Can be easily transported for use in home
visits .
• The level of cold generated can be adjusted
by the rate at which the button is
depressed.
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Cervical cryosurgery
• Cervical cryosurgery or cryotherapy is a
gynecological treatment that freezes a
section of the cervix.
• Is also used for the treatment of cervicitis
or inflammation of the cervix
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Cervical cryosurgery
• Cryosurgery is not a treatment for cervical
cancer.
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tumors of the bone
• destruction of nearby bone tissue
→fractures
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