Transcript Bioinformatics I

Bioinformatics I
Michael Schroeder
BioTechnological Center
TU Dresden
Biotec
Bioinformatics
BIOlogy
INFORmatics
matheMATICS
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Bioinformatics
Bioinformatics = Biological + Informatics - Logical
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How to teach bioinformatics
 Applied bioinformatics
 Use bioinformatics tools to answer biological questions
 Programming for bioinformatics
 Learn how to use databases and how to programme in
Python
 Term 3: Structural and computational biology
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Structure of module
 Overview
 A bit of everything
 A web tour:
 online resources for DNA and protein sequences, protein structures and
expression data
 Sequence comparison
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Dot plots
Dynamic programming
Substitution matrices
Multiple alignments
BLAST
PSI-BLAST
 Phylogeny
 Protein structure
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Practicals
 Two types:
 Bio: You’ll be given a biological questions and you’ll use online
resource to answer the question
 Computing: You learn about Unix and Python, however you need
to teach yourself, too. Please buy a Python book
 Each week you work through some questions during the lab and
do some homework
 Joachim Haupt and Janine Roy
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Assessment
 Written exam counting 80% of final mark
 Practicals: Test during lab (week 10) and homework counting
20%
 Test: Will involve using online tools and resources to answer
some questions
 Homework: you must pass at least 10 homework assignments
(there will be 13 overall). Passing means that >50% of your
answers are correct
 For homework you get pass/fail
 For the test you get a mark given that your homework is pass
 Strategy for preparation
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Buy book
Read book
Follow slides
Do all labs and homework
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Getting in touch
Email: [email protected]
Web site: http://www.biotec.tu-dresden.de/schroeder
Includes web site for bioinformatics modules
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Modules text book
 Chapter 1 is online at the
module web site
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