Transcript Eukaryotic Protein Networks

STRING examples
• Go to the STRING web site
http://string.embl.de
• Examples for “Protein mode”
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MURC_TREPA
ANP1_YEAST
• Lookup examples
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Judge the correctness of the
predictions
Use the evidence viewers to
understand the basis for the
predictions
• Feel free to also lookup proteins
that you are interested in or to
use the ”random” link
Lars Juhl Jensen, EMBL Heidelberg
• Examples for “COG mode”
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COG0055
COG1117
• Examples for comparing the two
different modes
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trpB
P91427
Examples for ab initio prediction methods
• Go to the following services
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GlobPlot
http://globplot.embl.de
DisEMBL
http://dis.embl.de
ELM
http://elm.eu.org
ProtFun
http://www.cbs.dtu.dk/services/
ProtFun/
• Submit the following examples
and interpret the results
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PRIO_HUMAN
P53_HUMAN
Lars Juhl Jensen, EMBL Heidelberg
• Go to the following services
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TargetP
http://www.cbs.dtu.dk/services/
TargetP/
PSORT
http://psort.nibb.ac.jp/
ExPASy ProtParam
http://www.expasy.org/tools/prot
param.html
• Try to predict the subcellular
localization of these calpains
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CANA_HUMAN
CAN1_HUMAN
(CAN2_HUMAN)