Transcript Slide

The Role of Bcl-xL in Mouse RPE Cell Survival
Invest. Ophthalmol. Vis. Sci.. 2011;52(9):6545-6551. doi:10.1167/iovs.10-6772
Figure Legend:
Survival factor gene expression after Bcl-xL inhibition. Pooled mRPE cells were transfected with 300 nM control ASO
and Bcl-xL–specific ASO. RNA was collected 4 days postplating and cDNA was synthesized. qRT-PCR was used to
determine gene expression of pro- and antisurvival factors. Gene expression of survival factor genes was normalized to
PPIA, a housekeeping gene for the mouse, and is relative to the expression of the control ASO-transfected Bcl-xL gene.
Data are presented as mean ± SD of three independent experiments. *P < 0.007 vs. Bcl-xL control ASO.
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