Transcript - Real Child Center

Principles of Homotoxicology
and How it Relates to the
Autistic Spectrum Disorder
Mary Coyle, D.I.Hom
Realchildcenter.com
[email protected]
Tel: 212-255-4490
Potential Contributors
Genetics
Biological
Triggers
Autism
Environmental Toxicity”
Heavy Metals/Pesticides
Chemicals/Air Pollution
Pharmaceutical Interventions
Toxins
Studies have confirmed
at least 250 chemical
contaminants are tucked
away in the body fat of
every person on the
planet
Toxic Exposures and Autism
An analysis of preconception histories
of 20 parents exposed to high amounts
of chemicals showed that the
significant difference in the parents of
children versus the control group was
their exposure to chemicals.
Biology of the Autistic Syndrome
TOXINS/HOMOTOXINS
What are Homotoxins?
Homotoxins are substances
toxic to humans.
Homotoxins reduce the
conductivity of the biological
terrain.
What Might Happen If Too Much Garbage Goes
IN to the Body, and Not Enough Goes OUT
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Oxidative Stress
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Reduction of Glutathione
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Mitochondrial Dysfunction
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Impaired Methylation System
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Gastrointestinal Issues
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Impaired Fuel Metabolism
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Inflammation
First Steps to Increase
Energetic Vitality
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Drink plenty of fresh, clean water
Ionized minerals
High-quality supplements
Tissue Salts
Reduce EMF stress; especially while sleeping
Balance pH
Remove offending food
Consume living food/high-quality organic food
(foods that do not promote inflammation)
Relax and spend (self-limiting) time in the sun
Immunology and Illness
Disorders of the immune system may occur for the following
reasons:
Pathogens and/or xenobiotics invade the immune system at
such a pace that the body is unable to recover.
Disordered immune response to antigens, such as allergies
(imbalance of the Th1/Th2)
Inherited or acquired immune deficiencies occur
Disordered immune response to self – as seen in autoimmune
diseases
Phenol Sulfur -Transferase (PST)
Enzyme Weakness
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Low Sulfation leads to poor detoxification of Phenols.
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PST Enzymes assist in the removal of phenolic
substances from the body
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Common Phenolic Substances
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Hormones
Salicylates (raspberries, apples, strawberries)
Biologic Agents (yeast) can produce phenols
Pesticides, Herbicides, Perfumes
Neurotransmitters such as Seratonin and Dopamine
The reduction of optimal sulfation may show as
fatigue, hyper-activity, self-stimulatory behaviors, red
cheeks, red ears.
“Saliva, pupil size difference
in autism show system in
overdrive”
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“University of Kansas researchers have found larger resting
pupil size and lower levels of a salivary enzyme associated
with the neurotransmitter norepinephrine in Children with
autism spectrum disorder”
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University of Kansas, Lawrence Campus, July 12, 2012
Our symbiotic relationship
with microbes
A healthy person maintains
a symbiotic relationship
with its internal microbial
environment. A weak and
compromised person is
unable to effectively
manage his/ her own
endogenous microbial loadwhich enables the internal
biological milieu to become
more opportunistic.
Hans Seyle
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Flight or Fight Response
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First Phase: Adaptation
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Second Phase: Alarm
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Third Phase: Exhaustion
ASD and Mitochondria
Disorders
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Mitochondria are organelles that function as the power house
of the cell. These energy packs reside in every cell of the body,
except the red blood cells, and generate adenosine
triphosphate (ATP) .
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Recent studies have challenged the “classical” definition of
mitochondrial dysfunction. They suggest that a subset of ASD
children may have a secondary form or mitochondrial
dysfunction - with may be related to toxic exposures.
Rossignol DA, Bradstreet J. Evidence of mitochondrial
dysfunction in autism and implications for treatment. Am J
Biochem Biotech. 2008; 4(2): 208-17.
Homotoxicology is a system
designed to ENABLE the Body to
REACT
The Question is: How does your child react to stress?
ASD and Cerebral Energy
Metabolism
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Research has shown that impaired cerebral energy and
phospholipid metabolism corresponds with neuropsychological
and language deficits frequently observed in the autistic
population.
Minshew NL et al. A preliminary P MRS study of autism:
Evidence of undersynthesis and increased degradation of brain
membranes. Biological Psychiatry 1993;33: 762 -73
What is Homeopathy?
Homeopathy is based on the concept Similia similibus curentur
('Let like be cured by like')
Beginning the Journey of
Homotoxicology
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The Model: Dr. Reckeweg theorized that all diseases may be
categorized under three processes.
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Excretion of the toxin: Such as diarrhea, skin eruptions,
mucous, fever, cough
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Deposition (deposits) of the toxins: Such as warts,
hemorrhoids, cysts
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Degeneration through the actions of the toxins: Such as
autism, diabetes, MS, lupus, cancer
Biologists Ludwig Von
Bertalanffy
At the turn of the century, biologist Ludwig Von Bertalanffy,
described every living system (man, bird, slug) as systems of
flowing elements, designed to gain and maintain balance.
Biotherapies
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Foundational remedies: water, air, light, magnetism, downtime, sleep
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Biochemical remedies: food, botanicals, enzymes, vitamins,
minerals
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Structural Remedies: massage, colonics, body work,
Cranial-Sacral, castor oil packs, hydrotherapy
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Energetic: Homeopathy, acupuncture, flower remedies,
Reiki, drainage remedies tissue salts, oligotherapy
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Mental and Spiritual Work
The Emunctories
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Primary Emunctories
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Lungs, Kidneys, Digestion
Tract/Liver, Skin, Emotions
Secondary Emunctories
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Skin, Musculo-skeletonal,
Mucous Membranes,
Emotional Changes
DRAINAGE
The physiological action that supports
the body to remove toxins, without
aggression, or pushing it to eliminate
beyond its physiologic ability. This
allows for self-regulation.
Drainage Remedies
Oligotherapy: The use of small concentrations of minerals which
serve to activate enzymes.
Gemmotherapy: The embryological tissue of plants which can be
used to support and drain a gland or tissue
Organotherapy: Dynamized and diluted organ tissue designed to
stimulate the corresponding organ tissue
Tissue Salts: Restores the proper balance of tissue salts (12) in
the body.
Flower Essences: Diluted extracts of flowers or plants designed to
address emotional and mental issues
5 Phases of Draining Toxic
Build-up
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1: Opening Eliminative Pathways
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2: Address Liver blockages
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3: Address Kidney and Respiratory Blockages
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4: Clean-up metabolic Waste
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5: Address further primary and secondary emunctories
Homeopathic Formulations
as Physiological Regulatory
Agents
These formulations are designed to restore physiology through
providing communication molecules such as hormones,
neuropeptides, interleukins and growth factors better
efficiency.
The Efficacy of Using Serial
Agitated Dilutions
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The effectiveness of homeopathic preparations was further
substantiated by a meta-analysis of 105 published studies
reviewing the efficacy of serial agitated dilutions (SAD). The
study concluded that 80% of the outcomes meeting the criteria
for meta-analysis were positive.
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Jonas W et al. Critical review and meta-analysis of serial
agitated dilutions in experimental toxicology. Hum Exp Toxicol.
1994 Jul;13(7):481-92
Potentized Low-Doses of a
Cytokine Solution and
Allergic Asthma
An oral administration of potentized low doses of cytokine
solutions not only resolved the bronchial hyper-reactive
response of the mice, but normalized the cytokine levels.
The study stated, “These findings may suggest a novel
approach to diseases that involve a Th1/Th2 imbalance.”
Gariboldi S et al. Low dose oral administration of cytokines for
treatment of allergic asthma. Pulm Pharmacol Ther, 2009
Dec;22(6): 497-510
Homeopathic Cellular Supports
Bio-energetic cellular support products supply the body the energy
it needs, without requiring additional reserves for break-down and
assimilation; which are necessary when functioning on the
bio-chemical level (digestion of food, supplements, etc.). They are
designed to stimulate the production of energy (ATP), and
promote cellular regeneration.
If the body is equipped with the energy it needs to begin
functioning properly, it will naturally start by “cleaning house” and
mobilizing the toxins towards excretion.
Low-Potency Homeopathic
Detoxification
It is a process of recognizing, neutralizing, and removing toxic
compounds.
The goal is be both dynamic and reactive to facilitate
homeostasis.
EnzymTes and Enzymatco-factors
“Enzymes
are the most important unit in the human body, because
every chemical change that takes place to repair tissue or to
assimilate food involves the activity of enzymes. Without enzyme
activity there is no life. No plant or animal can live without the
activity of its enzymes.” Dr Royal Lee
Epigenetics
(you’re not necessarily stuck
with this…)
Epigenetics means “above the gene.” Environmental factors such
as stress, diet, and toxins may alter gene(s), but may not have
caused a permanent mutation to the gene(s).
Epigenetics and the
Agouti Mice
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These mice have a genetic defect in their agouti gene which codes
the signaling molecule to produce a yellow coat, obesity,
hyperinsulinemia and the susceptibility to cancer. Feeding the
females a methyl-supplemented diet produced a greater number
of normal offspring.
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FASAB j. 1998 Aug:12 (11): 949-57.
DNA Repair Enzyme
Mechanisms
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Termed “Molecule of the Year” these enzymes scan our DNA and
repair nucleotides which may have been incorrectly sequenced
due exposures for either pathogens or xenobiotics
Cellular Supports and DNA Repair
Enzymes
✴ “Like doctors making house calls, some DNA repair enzymes
can relocate to the part of the cell that needs their help. A
collaborative team of scientists of Emory University School of
Medicine has found the signal that prompts relocation is
oxidative stress, an imbalance of cellular metabolism
connected with several human disease.”
Molecular and Cellular Biology, Feb 1, 2009 issue
“DNA Repair Enzymes Relocate in Response to Stress,” Vincent
Dollard.
The Neuroplasticity of the
Brain
This study involved mice with a genetically induced
neurodegenerative disease that progressed into significant
brain atrophy and neuronal loss. The mice presented with
long-term memory loss and severe learning impairment. When
exposed to an enriched environment, they began developing
neuronal dendrites, increasing the number of synapses,
improved learning capacity, and regained long-term memory
loss.
Nature. 2007 May 447:178-82
Bringing Hope…
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“Their genome they inherit - But their epigenome, they
potentially can alter, and particularly that of their children. And
that brings in responsibility, but it also brings in hope. You're
not necessarily stuck with this. You can alter this.”
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DR. RANDY JIRTLE
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“Ghost in Your Genes” NOVA