Transcript Agilent: The Company, The Myth, The Lengend

Agilent: The Company,
The Myth, The Lengend
Agilent:



Agilent Technologies Inc. (NYSE: A) is a world-wide, diverse technology
company focused on expansion into software, chemical analysis, electronics,
and life sciences markets.
The company operates four businesses -- test and measurement, automated
test,
semiconductor products, and life sciences and chemical analysis -- all
supported by
a central research group, Agilent Laboratories.
In particular, Agilent provides software designed to facilitate analysis of
microarray data. The GeneSpring platform allows the investigator to
formulate biologically relevant inferences- via comparative analysis of
expression data, genotyping, protein, metabolite and other data types- with
higher degrees of confidence.
Agilent: GeneSpring (Features)

Unearths correlations between Expression Profiles and
Experimental Parameters:
Investigators can devise complex experiments and generate convenient display of data that correlate
trends in expression to a wide variety of test parameters.
Subsequent analysis can be conveniently refined to test hypotheses by re-computation of previously
defined analyses against alternative combinations of samples.
In this way, researchers can determine relevant experimental parameters, for genes showing
differential expression patterns, to help elucidate causative relationships.
Agilent: GeneSpring (Features)

Advanced Statistical Tools:
The GeneSpring platform provides a multitude of statistical applications which include t-tests, 2-way
ANOVA tests and 1-way post-hoc tests for dependably identifying differentially expressed genes.
GeneSpring GX class prediction tools can group gene, identified via expression profiling, by
discriminating between one or more experimental parameters or sample phenotypes.
Furthermore, gene sets can be further characterized by performing sequence searches for potential
regulatory elements.
Agilent: GeneSpring (Features)

Data Clustering:
GeneSpring GX provides state of the art clustering methods to reveal patterns of gene expression.
Researchers can utilize one or a combination of clustering options to typify trends in their data:
Self-Organizing Maps (SOM), k-means, gene trees (hierarchical clustering), Principal Components
Analysis (PCA) and QT clustering.
In particular, Principal Components Analysis (PCA), allows the investigator to lessen the complexity of
data by revealing a number of principal components that account for most of the data variability.
Agilent: GeneSpring (Features)

3D Data Visualization:
The 3D scatter plot tool offers detailed interactive views of complex data.
Data quality can be optimized by plotting average expression values for each gene
cluster in a scatter plot to reduce noise and rapidly identify patterns in expression data.
Agilent: GeneSpring (Features)

Pathway Views:
Built-in the GeneSpring platform is the tool called the pathway viewer, in which genes
and their expression patterns can be visually differentiated based on their location within
a metabolic pathway.
Using pathway viewer investigators can predict which genes will be associated with
discrete steps in the pathway of interest.
Furthermore users can design their own pathway architecture
Agilent:



Chief Executive Officer (CEO): William P. Sullivan
President, Chief Executive Officer, Director
Experience: Prior to his appointment in March 2005, Sullivan was the company's
executive vice president and general manager.
Sullivan was senior vice president and general manager of Agilent's Semiconductor
Products Group (SPG). He joined Hewlett-Packard Company in 1976 and during the
course of his career, developed considerable expertise in telecommunications, data
communications and computers. In 1995, he was promoted to general manager of the
Optical Communication Division, and two years later was named general manager of the
Communication Semiconductor Solutions Division.
Financial summary and projected market:
Net Revenue (FY04)
U.S. $7.2 billion
Products marketed to scientific community.
Agilent Corporation Location: Headquarters
Palo Alto, California

Company Alliances: Hewlett-Packard, Amgen, Academia
Agilent:


Profitability: The company returned to profitability in the fourth quarter of
fiscal 2003 and generated more than $700 million in cash in 2004.
Stock price fluctuations over two years:
Agilent:


Agilent wants scientists from many
fields.
In my estimation Agilent is likely to
remain profitable for many years to
come.