Pedigrees - Cloudfront.net

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Transcript Pedigrees - Cloudfront.net

Pedigrees
Pedigrees are used to:
– Determine whether a trait is inherited
– Show how a trait is passed from one
generation to the next
– To determine if an allele is dominant
or recessive
Symbols:
• Female
• Male
Connecting Symbols:
• Married Couple
• Siblings
Generations
I
II
III
Symbols:
• Affected
• Carrier
• Deceased
Sex-linked:
Sex-linked issues…
• Are caused by genes located on X or Y
chromosome
• More common in males since they have
only 1 X chromosome; females more often
carriers
• Female must have 2 recessive genes for
trait to occur
Karyotypes
• To look for nondisjunction
(chromosomes fail to separate) or
other genetic disorders
Karyotypes
• To look for nondisjunction
(chromosomes fail to separate) or
other genetic disorders
Accessing Genetic
Disorders
• Analyzing pedigrees
• Genetic counseling
• Prenatal testing