Transcript NF-κB IN CANCER: FROM INNOCENT BYSTANDER TO MAJOR

NF- B IN CANCER:
FROM INNOCENT
BYSTANDER TO MAJOR
CULPRIT
Nature Reviews Cancer
2, 301-310 (2002)
The IKK complex controls two distinct
NF-kB activation pathways
NF-kB contributes to the induction of
four classes of genes
Different mechanisms by which NF-kB
activation can contribute to leukaemia and
lymphogenesis
Signalling pathways that stimulate the proliferation
of mammary epithelial cells by induction of cyclin
D1 gene transcription
Role of NF-kB in gastric and colorectal
cancers
NF-kB and IkB proteins