Transcript Muscular Dystrophy Disease/MD

Muscular Dystrophy
Disease/MD
Iyana Gifford
Psychology
3rd period
Cause
MD is a disease in which muscles of the body that gets weaker and weaker,
and slowly stops working.
Transmission
This disease affects both men and
women. Genetically inherited from
parents and you were born with it.
MD is a recessive trait. MD
normally produces a protein called
dystrophin, which helps muscle
cells keep their normal shape and
function. The gene that causes
muscular dystrophies either does
not produce enough dystrophin or
produces dystrophin that doesn't
work properly. This gene is
located on the X chromosome.
Women don't usually get it as
much as men because Women
have two X chromosomes,but
men have only one X
chromosome (men also have a Y
chromosome, which
(men also have a Y chromosome,
which does not have a copy of the
dystrophin gene).
Girls don't usually get the disease
because the healthy gene on one
X chromosome can produce
enough normal dystrophin to
compensate for the defective gene
on the other X chromosome.
Symptoms
There are nine different types of Muscular Dystrophies and the
symptoms usually appear in early/late childhood to early
adulthood. Pain is sometimes a symptom of each, usually due to
the effects of weakness on joint position. It can occur in your
hips, legs, and feet, t
he weakness in the joints make it hard to walk and stand up
sometimes. The calf may swell because of contractures (muscle
tightness). It can also occur in the shoulders, upper-arm, and
hands. Scoliosis may occur, but is usually milder and progresses
more slowly .Respiratory weakness also occurs, heart muscle
disease (cardiomyopathy), problems may include irregular
heartbeats and congestive heart failure. Other symptoms in the
body may include fatigue, shortness of breath, chest pain, and
dizziness.
Prognosis
Some patients have only mild symptoms with a normal
lifespan. Others have severe symptoms and die at a
young
age.
Cure..
There's currently no cure for any form of
muscular dystrophy.Research into gene
therapy may eventually provide treatment
to stop the progression of some types of
muscular dystrophy. But of course there is
therapy to make the joints and muscles
stronger.
Citations
Quercia, Nada. "Muscular Dystrophy." The Gale Encyclopedia of Genetic Disorders. Ed. Brigham Narins. 2nd ed. Vol. 2. Detroit:
Gale, 2005. 861-869. Gale Virtual Reference Library. Web. 8 Mar. 2013
http://www.humanillnesses.com/original/images/hdc_0001_0002_0_img0183.jpg
http://www.lehman.cuny.edu/faculty/jfleitas/bandaides/jonprom.jpg
http://www.mayoclinic.com/health/muscular-dystrophy/DS00200/DSECTION=treatments-and-drugs