STANYSintro2005
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Teaching Biology Through
Bioinformatics
Real world genomics research
in your classroom
Kim B. Foglia
Stuart M. Brown, PhD
Division Ave. High School
AP Biology
Levittown
Director of Research Computing
2004-2005
NYU School of Medicine
Bioinformatics
Use of computers to analyze genomic
data for molecular biology research
basic biological research
medical research
clinical medicine application
taxonomy
Bioinformatics
2005-2006
Bioinformatics is a great way
to learn biology
Using computers to study primary
biological data (genomes, proteins,
other databases)
students learn biology as a dynamic
process of interpreting complex data
students can reproduce current scientific
work & ask new questions
science is no longer just a collection of facts
in a textbook, it’s a process of inquiry
Bioinformatics
2005-2006
Teaching Biology with Bioinformatics
Bioinformatics tools lead directly to
insights about genes, proteins, evolution
“Hey! Most human genes have more
bases of introns than they do exons.”
“Hemoglobin sequences show that seals
are closer to weasels than they are to
whales.”
“Protein shapes determine their function,
so small changes can make a big
difference.”
Bioinformatics
2005-2006
All you need…
Students can work on
bioinformatics questions at low cost
only need Internet connected computers
most database tools are free on Internet
unlimited data
GenBank, protein structures, mutations,
microarrays, etc.
teacher knowledge & “comfort”
questions to answer
Bioinformatics
2005-2006
What we offer…
Teaching modules
inquiry labs
student & teacher lab handouts
supporting teaching resources
PowerPoint presentations
Supplemental skills modules
Download from Web site
http://bio.kimunity.com
Bioinformatics
2005-2006
Modules in development
Testing for Sickle Cell Anemia
develop a genetic diagnostic test to
screen for disease
Endosymbiosis
evolutionary history mitochondria &
chloroplasts
Hemophilia Gene Therapy
build a vector and insert correct gene
Are Seals and Whales Related?
studying evolutionary relationships
Bioinformatics
2005-2006