Transcript The Biotechnology Century and Its Workforce

Active Lecture
Questions
Chapter 19
Disorders
Associated with the
Immune System
Copyright © 2010 Pearson Education, Inc.
Desensitization to prevent an allergic
response can be accomplished by
injecting small, repeated doses of
a.
b.
c.
d.
e.
IgE antibodies.
the antigen (allergen).
histamine.
IgG antibodies.
antihistamine.
What does “pluripotent” mean?
a. Ability of a single cell to develop into an embryonic or
adult stem cell.
b. Ability of a stem cell to develop into many different cell
types.
c. A cell without MHC I and MHC II antigens.
d. Ability of a single stem cell to heal different types of
diseases.
e. Ability of an adult cell to become a stem cell.
Cytotoxic autoimmunity differs from
immune complex autoimmunity in that
cytotoxic reactions
a.
b.
c.
d.
e.
involve antibodies.
do not involve complement.
are caused by T cells.
do not involve IgE antibodies.
none of the above
Antibodies against HIV are ineffective for
all of the following reasons except
a. the fact that antibodies aren’t made against
HIV.
b. transmission by cell–cell fusion.
c. antigenic changes.
d. latency.
e. persistence of virus particles in vacuoles.
Which of the following is not the cause of
a natural immunodeficiency?
a. a recessive gene resulting in lack of a thymus
gland
b. a recessive gene resulting in few B cells
c. HIV infection
d. immunosuppressant drugs
e. none of the above
Which antibodies will be found naturally
in the serum of a person with blood type
A, Rh+?
a.
b.
c.
d.
e.
anti A, anti B, anti Rh
anti A, anti Rh
anti A
anti B, anti Rh
anti B
What type of hypersensitivity is due to
localized anaphylaxis.
a.
b.
c.
d.
e.
type I hypersensitivity
type II hypersensitivity
type III hypersensitivity
type IV hypersensitivity
all of the above
What type of hypersensitivity is due to
allergic contact dermatitis.
a.
b.
c.
d.
e.
type I hypersensitivity
type II hypersensitivity
type III hypersensitivity
type IV hypersensitivity
all of the above
What type of hypersensitivity is due to
immune complexes.
a.
b.
c.
d.
e.
type I hypersensitivity
type II hypersensitivity
type III hypersensitivity
type IV hypersensitivity
all of the above
What type of hypersensitivity is due to a
reaction to an incompatible blood
transfusion.
a.
b.
c.
d.
e.
type I hypersensitivity
type II hypersensitivity
type III hypersensitivity
type IV hypersensitivity
all of the above
Hypersensitivity refers to an
a.
b.
c.
d.
Allergen
Antibody
Immunity
Altered antigenic response
What is the mediator of an allergic
reaction stored in granules?
a.
b.
c.
d.
Histamine
Prostaglandins
Leukotrienes
Acetylcholine
Which of the following can result from
systemic anaphylaxis?
a.
b.
c.
d.
Contact dermatitis
Hives
Shock
Asthma
What is the approximate percentage of
autoimmune disease cases that affect
women?
a.
b.
c.
d.
75%
50%
60%
30%
Which antibodies are associated with
autoimmunity?
a.
b.
c.
d.
IgG and IgM
IgA
IgD
IgE
A person with which of the following
develops a goiter and markedly bulging
eyes?
a.
b.
c.
d.
Multiple sclerosis
Graves’ disease
Psoriasis
Hepatitis C
When a monoclonal antibody is
combined with a toxic agent, it forms a(n)
a.
b.
c.
d.
Activated antibody
Immunotoxin
Probe
Tumor necrosis factor
When does a person manifest a
hypersensitive reaction?
a.
b.
c.
d.
On primary exposure
On a second or subsequent exposure
During immunosuppression
During an autoimmune disease
Which of the following increases a
person’s susceptibility to certain cancers?
a.
b.
c.
d.
Immunosuppression
Immunologic surveillance
Immunologic enhancement
Cytotoxic destruction
A promising new technique for analyzing
HLA is the use of a(n)
a.
b.
c.
d.
Precipitation reaction
Neutralization reaction
Polymerase chain reaction
Agglutination reaction
Xenotransplanation products are tissues
or organs transplanted from
a.
b.
c.
d.
Animals
An identical twin
Yourself
Another human
What type of response do the
immunocompetent cells in transplanted
bone marrow mount against the tissue
into which they have been transplanted?
a.
b.
c.
d.
Cell-mediated immune response
Humoral immune response
Hyperacute response
Hypersensitive response
The primary mode of transmission of
HIV worldwide is
a.
b.
c.
d.
Respiratory
Blood
Homosexual transmission
Heterosexual transmission
HIV is able to evade immune defenses
by
a.
b.
c.
d.
Undergoing rapid antigenic changes
Producing a lot of antibody
Killing the host cells
Becoming latent
What percentage of infants born to HIVpositive mothers are born infected?
a.
b.
c.
d.
50%
20%
30%
60%