Transcript Mendel Discovers “Genes” 9-1

Exploring Mendelian
Genetics
11-3
http://www.eslkidstuff.com/images/tallshort.gif
http://sps.k12.ar.us/massengale/genetics%20tutorial.htm
GENES are more complicated
than Mendel thought
ENVIRONMENT influences the
____________________________
________________________.
expression of genes
“Nature vs Nurture”
= ________________________
provide the plan
Genes ________
______ for
development, but how plan unfolds also
depends on ______________conditions.
environmental
_______
GENES are more complicated
than Mendel thought
Some traits have
choices
____________
MORE than 2 allele __________
MULTIPLE ALLELE TRAIT
= ____________________
EX: blood type
B ___
O
A ___
Allele choices ___
GENES are more complicated
than MENDEL thought
Some traits are determined by
____________________________
MORE THAN ONE GENE
POLYGENIC TRAIT
= __________________
EX: human height.
intelligence,
skin & eye color
http://www.bcps.org/offices/lis/models/life/images/grow.JPG
GENES are more complicated
than MENDEL thought
Traits determined by ____________
MORE than
ONE
gene have _____
_________
many
“___________”
in-between phenotypes
There aren’t just SMART people
and DUMB people….
there is a ________________
whole range
of intelligences in-between
http://www.newtonswindow.com/problem-solving.htm
GENES are more complicated
than MENDEL thought
KINDS OF DOMINANCE
____________________
COMPLETE DOMINANCE
INCOMPLETE DOMINANCE
____________________
CO-DOMINANCE
____________________
COMPLETE DOMINANCE
Dominant allele _______
masks
__________
the ___________
recessive one
PATTERN ?
Recessive allele
____________
________
returns
in a _____ratio
in the
3:1
____
F2 generation
http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookTOC.html
INCOMPLETE DOMINANCE
DON’T
SEE expected
__________
_____
3:1 ratio in
F2 generation
Heterozygous organisms with one
_____________
dominant and one recessive allele
show a _________
BLENDED in-between trait
Image modified from: http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookTOC.html
CO-DOMINANCE
BOTH traits are expressed at ___________
_______
SAME TIME
(_____________________)
in heterozygote
NO BLENDING
ROAN
A ________HORSE
has
______________
BOTH RED hair
and __________
WHITE hair
side by side
CO-DOMINANCE
Both traits are expressed together
(NO BLENDING) in heterozygote
Persons with an A allele
AND a B allele have
blood type AB
REMEMBER
Membrane proteins with
_______
sugars attached that
help cells recognize self
= ______________
GLYCOPROTEINS
http://www.mannanw.com/super-sugars.htm
BLOOD TYPES
have more than 2 allele choices
MULTIPLE ALLELE TRAIT
= _________________________
The pattern of sugars that is
attached is determined by genes
Allele choices are:
A
B
O
_____
____
____
BLOOD TYPES
An A allele tells
the cell to put
“A” glycoproteins
on its surface
BLOOD TYPES
A B allele tells
the cell to put a
different “B”
glycoprotein
on its surface
BLOOD TYPES
An O allele tells
the cell NOT to put
anything on the
surface
A and B are CO-DOMINANT
A cell with
BOTH an
A and a B allele
has BOTH
“A” and “B”
glycoproteins on its
surface
BLOOD TYPES & ALLELES
GENOTYPE
AA
AO
BB
BO
OO
AB
PHENOTYPE
(BLOOD TYPE)
A
A
B
B
O
AB
DONOR
BLOOD
A and AB see A
as “like me”
Body images modified from:
http://www.new-fitness.com/images/body_shapes.jpg
B and O see A
as Different!
IMMUNE SYSTEM
ATTACKS!
DONOR
BLOOD
B and AB see B
as “like me”
Body images modified from:
http://www.new-fitness.com/images/body_shapes.jpg
A and O see B
as Different!
IMMUNE SYSTEM
ATTACKS!
DONOR
BLOOD
O can donate to
____
EVERY BLOOD TYPE
= _____________________
UNIVERSAL DONOR
Nothing on surface to
recognize as “NOT SELF”
YOU DON’T HAVE
ANYTHING I DON’T
HAVE!
Body images modified from:
http://www.new-fitness.com/images/body_shapes.jpg
DONOR
BLOOD
Only AB sees AB
as “like me”
Body images modified from:
http://www.new-fitness.com/images/body_shapes.jpg
A, B, and O see
AB as Different!
IMMUNE SYSTEM
ATTACKS!
AB can only GIVE to AB
BUT . . .
AB can RECEIVE FROM
______
EVERY BLOOD TYPE
= ________________________
UNIVERSAL RECIPIENT
Body image modified from:
http://www.new-fitness.com/images/body_shapes.jpg
BLOOD TYPE FREQUENCY
IN USA
A
B
AB
O
40%
10%
4%
46%
http://www.reachoutmichigan.org/funexperiments/agesubject/lessons/newton/BldTyping.html
ABO SYSTEM is NOT
THE ONLY ONE
+
Rh
Rh
OTHER BLOOD TYPES
____________________
IF:
NO PROBLEMS
Rh+
MOM is _____
& BABY is _____
Rh+
Image modified from:
http://www.wsd1.org/lessonplans/images/Body.gif
MOM is _____
Rh+
& BABY is ____
Rh-
PROBLEM IF:
Can be a ___________
Mom is _____
Rh-
Baby is _____
Rh+
1st baby OK but few baby cells
entering mom’s bloodstream
put mom’s immune system on
alert for + cells.
Next + baby, mom’s immune
system can attack baby as it is
growing
Mom given shot after 1st birth
prevents this
Image modified from:
http://www.wsd1.org/lessonplans/images/Body.gif
DIHYBRID CROSSES
(2
traits)
http://mac122.icu.ac.jp/BIOBK/BioBookgenintro.html
Mendel also asked the question?
Does the gene that determines if a seed
is round or wrinkled have anything to
do with the gene for seed shape?
Must a seed that is yellow
also be round?
MAKING A CROSS with
TWO gene traits
___________________=
DIHYBRID
CROSS
____________________
A Punnett square for
a DIHYBRID
CROSS looks like
this:
Figure 11-10 Independent Assortment in Peas
Section 11-3
Go to
Section:
LET’S MAKE A DIHYBRID CROSS
HOMOZYGOUS
YELLOW ROUND
RRYY
HOMOZYGOUS
GREEN WRINKLED
rryy
1. Figure
___________
are
out what _________________
parent alleles
2. Choose
________correct__________
Punnett square __________
size
3. Put
______
in possible_______________________
parent gametes
4. Fill
______
in boxes with _____________________
offspring combinations
5. Determine ____________of_____________&
probabilities phenotypes
____________
genotypes
LAW OF
INDEPENDENT ASSORTMENT
__________________________
the factors are distributed to gametes
independently of other factors
Image modified from:
http://anthro.palomar.edu/mendel/mendel_1.htm
PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES
THIS PARENT CAN MAKE?
HOMOZYGOUS
ROUND YELLOW
Each gamete should
get one of each kind
of gene
R RYY
R
Y
R
Y
RY
___________ ____________ _____________
RY
_____________
PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES
THIS PARENT CAN MAKE?
HOMOZYGOUS
WRINKLED GREEN
Each gamete should
get one of each kind
of gene
rryy
r
y
r
y
ry
___________ ____________ _____________
ry
_____________
PRACTICE MAKING GAMETES
WHAT ARE THE POSSIBLE GAMETES
THIS PARENT CAN MAKE?
HETEROZYGOUS
ROUND YELLOW
Each gamete should
get one of each kind
of gene
RrYy
R
Y
r
y
rY
___________ ____________ _____________
Ry
_____________
ry
ry
ry
ry
RY
RrYy
RrYy
RrYy
RrYy
RY
RrYy RrYy
RrYy
RrYy
RY
RrYy
RrYy
RrYy
RrYy
RY
RrYy
RrYy
RrYy
RrYy
RrYy genotype
100% of offspring = _______
ROUND YELLOW phenotype
_______________________
MAKE ANOTHER CROSS
HETEROZYGOUS
ROUND YELLOW
RrYy
X
HETEROZYGOUS
ROUND YELLOW
RrYy
POSSIBLE PARENT GAMETES?
RY
ry
rY
Ry
RY
Ry
rY
ry
RRYY RRYy RrYY RrYy
____
9 Round &
Yellow
Ry
RRYy
3 Round &
____
green
rY
RrYY RrYy
RY
ry
RrYy
RRyy
Rryy
RrYy
Rryy
rrYY rrYy
3 Wrinkled
____
& yellow
rrYy
1 wrinkled
____
& green
rryy
heterozygous dihybrid cross is a
Sign of a ______________________
_____________
9:3:3:1 ratio in offspring.
____
9 ____________
dominant TRAIT 1 ; ____________
dominant TRAIT 2
3 ____________
dominant TRAIT 1; _____________
recessive
____
TRAIT 2
____
TRAIT 2
recessive TRAIT 1; _____________
dominant
3 ____________
____
TRAIT 2
1 ____________
recessive TRAIT 1; _____________
recessive
9:3:3:1
__________ratio
is a clue that it’s a
____________________________cross
HETEROZYGOUS TWO gene
PRACTICE MAKING GAMETES
for DIHYBRID CROSSES
http://www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBookTOC.html
What are the possible gametes?


RRTT
pure round & pure tall = __________
____
R T ____
R T _____
R T ______
RT
What gametes can it produce?
TtRR
Heterozygous Tall = __________
& pure round


What are the possible gametes?
____
T R ____
t R _____
t R ______
TR
What gametes can it produce?
What are the possible gametes?
Ttrr
= __________


Hybrid tall
& pure wrinkled
____
T r ____
t r _____
t r ______
Tr
What gametes can it produce?
What are the possible gametes?
tRr
=T
__________


Heterozygous tall
& hybrid round
____
T R ____
t r _____
t R ______
Tr
What gametes can it produce?