Transcript Pedigrees and Karyotypes

Pedigree
Analysis
Steps:
•Identify all people who have the
trait.
•For the purpose of this class all
traits will be given to you. In
ff
other instances, you would have
to determine whether or not the
trait is autosomal dominant,
autosomal recessive, or sexlinked.
Ff
•Identify all genotypes of this
family
•F- Normal
•f- cystic fibrosis
ff
Key:
ff
affected male
unaffected male
Ff
Ff
affected female
unaffected female
PKU
Pp
Pp
P- Unaffected
p- phenylketonuria
P-
pp
pp
P-
pp
Pp
Pp
hh
H-huntington’s
disease
Hh
h-Unaffected
Hh
hh
Hh
hh
Hh
hh
hh
Sex-Linked Inheritance
Colorblindness
XBY
XbY
XBXb
XbXb
XBXb
XbY
XbY
In other instances,
you would have to
determine whether
or not the trait is
autosomal dominant,
autosomal recessive,
or sex-linked.
Is this trait…
• autosomal dominant?
• autosomal recessive?
• X-linked dominant?
• X-linked recessive?
• Y-linked?