Age-Related Macular Degeneration (AMD)
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Transcript Age-Related Macular Degeneration (AMD)
Juvenile Macular
Degeneration
Lauran Maestas
Meghan Raney
Cressie Wright
Three major forms of Juvenile Macular
Degeneration
Best’s Disease
Juvenile Retinoschisis
Stargardt Disease
All are rare and cause central vision loss
Stargardt Disease
First report in 1901
German Ophthalmologist
Karl Stargardt
1997 genetic component discovered
Recessive gene
Both parents must have
Stargardt Gene
Normal
Gene produces
protein
Protein produces
energy
Energy sent to the
photoreceptor cells
Stargardt
No protein produced
Without protein no energy
No energy photoreceptor
cells in retina degenerates
Effects of gene defect
Fatty yellow pigment (Lipofusion)
Build up under cells in macula
Rods and Cones are affected
Atrophy in the macula
Loss of central vision
Blindness
Symptoms
Visual Acuity
20/40
20/200
Central Vision Loss
Vision Acuity
Blurry Vision
Distorted Vision
Symptoms
Dark Areas
Color Perceptions
Central Scotoma
(Blind Spot in
Central Vision)
Night Blindness
Photophobia
(Abnormal tolerance
for light)
Treatments
No Cure
Current research:
UV Protective glasses may slow the progression
Limit intake of vitamin A
Stem cells in adult body fat
References
Stargardt Disease. (n.d.). American Macular Degeneration Foundation |. Retrieved July 11, 2014, from
https://www.macular.org/stargardt-disease
Stargardt macular degeneration. (2014, July 7). Genetics Home Reference. Retrieved July 11, 2014, from
http://ghr.nlm.nih.gov/condition/stargardt-macular-degeneration
Kinkade, D. R. (2012, November 6). Low Vision Eyeglasses LowVisionEyeglasses.com: Guide to Macular Degeneration:
Short Answers to Complex Questions. Low Vision Eyeglasses LowVisionEyeglasses.com: Guide to Macular Degeneration:
Short Answers to Complex Questions. Retrieved July 11, 2014, from
http://lowvisioneyeglasses.blogspot.com/2012/11/guide-to-macular-degeneration-short.html
Stargardt Disease. (2014, November 7). . Retrieved July 11, 2014, from http://www.retina-international.org/eyeconditions/retinal-degenerative-conditions/stargardt
Grossman, M. (2013, August 28). Stem Cells Discovered in Fat May Treat Macular Disgeneration, Retinitis Pigmentosa,
Stargardt's. Eye conditions, eye care & diseases, treatment solutions. Retrieved July 11, 2014, from
http://www.naturaleyecare.com/blog/stem-cells-fat/
Grossman, M. (n.d.). Stargardt's Disease. Eye Care. Retrieved July 11, 2014, from http://www.naturaleyecare.com/eyeconditions/stargardts/
Age-Related Macular
Degeneration
(AMD)
Lauran Maestas
Meghan Raney
Cressie Wright
What is Age-Related Macular
Degeneration (AMD)?
AMD is a condition that causes central vision loss
AMD is the leading
cause of vision loss for
people over the age of 60
Two Forms of AMD
Dry Age-Related Macular Degeneration
More common
Develops slowly
Wet Age-Related Macular Degeneration
More severe
Develops quickly
Causes of AMD?
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Causes are unknown but possible risk factors
include:
Smoking
Obesity
Poor Diet
Exposure to UV
light
•
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High Cholesterol
Hypertension
Hereditary
Race
Gender
Symptoms of AMD
Blurriness
Wavy Lines
Blind Spot
http://www.preservision.com/en/what-is-amd/visionsimulator/
Dry AMD
Usually affects both eyes
Light Sensitive cells in the macula begin to
breakdown and die
Presents of Drusen
yellow spots under the retina
Photograph
of a healthy
eye
Photograph
of an eye
with dry
AMD
Wet AMD
Abnormal blood vessel growth
Blood and fluid leak under the macula
Leads to scarring
Photograph
of a healthy
eye
Photograph
of an eye
with wet
AMD
Treatments
Dry AMD
Wet AMD
No cure or treatments
Vitamins
Some studies show
specific combinations
of vitamins can slow the
progression and impact
No cure
Treatments
Injections into the eye
Photodynamic Therapy
Laser Therapy
Tools to Detect Progression of AMD
The Amsler Grid is a simple test to detect
early signs of AMD
Demonstration of Reduced Visual Acuity
http://www.lucentis.com/get-support
Case Study: Ernest Smith
Age-Related Macular Degeneration
Advanced Wet AMD in OS
Caused by oxidative stress
Used optical coherence tomography test
Treatment available: Thermal Laser Therapy
Daily monitor: Amsler Grid
Had to have treatment again
References
About wet AMD. (n.d.). What is Wet AMD. Retrieved July 15, 2014, from
http://www.lucentis.com/information/wet-age-related-macular-degeneration
Boyd, K. (2013, September 1). What Is Age-Related Macular Degeneration?. - Eye M.D.-approved
information from EyeSmart. Retrieved July 15, 2014, from
http://www.geteyesmart.org/eyesmart/diseases/age-related-macular-degeneration/index.cfm
Wet macular degeneration. (n.d.). Definition. Retrieved July 15, 2014, from
http://www.mayoclinic.org/diseases-conditions/wet-macular-degeneration/basics/definition/con20043518
What is Age-Related Macular Degeneration (AMD)?. (n.d.). Bausch + Lomb. Retrieved July 15, 2014,
from http://www.preservision.com/en/what-is-amd/what-is-amd/
WHAT IS AMD?. (n.d.). What is Age-Related Macular Degeneration?. Retrieved July 15, 2014, from
http://www.amdawareness.org/asrs/what-is-amd