Transcript Weather Forecasting Web Quest

2/27/14
111th Day of School
Learning goal (7.L.2.2 & 7.L.2.3): I will be able to
describe Huntington’s disease and use a Punnett
square and a Pedigree to track inheritance of such
genetic disorders.
Due Today: Late work
Evening Assignment: Study for vocabulary quiz!
Hawley Hornets Team
Dr. Batten
Shon B.
Justice N.
Logan Jacobi
Cody Wilkins
Ethan Batten-Hicks
$200 from Hawley!!!
$650 Total raised so far
A way you and your family can help fund research to fight childhood
cancers:
Donate at least $1 dollar to the Hawley Hornets team. Homeroom
teachers will collect your donations until Friday.
*** all donations are tax deductible ***
St. Baldrick’s Cancer Research Fundraiser
1. The grandfather in this family was a “high risk”
individual. How many of his children were either
medium or high risk individuals? How many of his
grandchildren were either medium or high risk?
2. Did the number of “medium risk” & “high risk”
individuals decrease or increase over subsequent
generations? Why do you think that happened?
3. If a parent is diagnosed with heart disease, does that
mean the children will have it also? Defend your answer.
With your partner write the answers to the above questions
on the back of your Pedigree chart.
Do Now: Group Discussion
1. The grandfather in this family was a “high risk” individual. How many of his
children were either medium or high risk individuals? How many of his
grandchildren were either medium or high risk? Each group will have
different results.
2. Did the number of “medium risk” & “high risk” individuals decrease or
increase over subsequent generations? Decrease Why do you think that
happened? Risk of inheriting heart disease from an affected individual
decreases through the generations because it is unlikely that all of the
necessary risk factors (genes) will be passed down to less closely related
family members.
3. If a parent is diagnosed with heart disease, does that mean the children will
have it also? Not necessarily. Defend your answer. Because heart
disease does have a genetic component, children of an affected parent
have an increased risk of developing heart disease relative to the
population at large.
Do Now: Group Discussion
Huntington’s Disease Video
http://youtu.be/4HgFUvVyHYQ
Description: Huntington’s Disease is a DOMINANT genetic disorder passed
down through families in which nerve cells in certain parts of the brain waste
away, or degenerate. Characterized by jerking uncontrollable movement of the
limbs, trunk, and face (chorea); progressive loss of mental abilities; and the
development of psychiatric problems.
Cause: Huntington's disease is caused by a genetic defect on chromosome 4.
The defect causes a part of DNA, called a CAG repeat, to occur many more
times than it is supposed to. Normally, this section of DNA is repeated 10 to 28
times. But in persons with Huntington's disease, it is repeated 36 to 120 times.
Inheritance: If one of your parents has Huntington's disease, you have a 50%
chance of getting the gene for the disease. If you get the gene from your
parents, you will develop the disease at some point in your life, and can pass it
onto your children. If you do not get the gene from your parents, you cannot
pass the gene onto your children. In autosomal dominant inherited disease, a
single abnormal allele is inherited from one parent. Any child, male or female,
with one affected parent has a 50% chance of inheriting Huntington's disease.
Incidence: One in every 10,000 persons—nearly 30,000 in the United States—
have Huntington's disease. Juvenile Huntington's occurs in approximately 16%
of all cases. Huntington's disease is not prevalent within any particular
population. All races and ethnic groups, and both sexes are affected.
Treatment: There is no cure for Huntington's disease. Treatment focuses on
reducing symptoms, preventing complications, and providing support and
assistance to the patient and those close to him or her.
Huntington’s Disease
What are the phenotypes of the children?
What are the chances of a child getting Huntington’s Disease?
How do you know that it is a dominant disorder?
Punnett Square for Huntington’s Disease
50%
75%
What are the chances of a child getting Huntington’s Disease?
Phenotypes: Healthy (hh) or have Huntington’s Disease (HH or Hh)
How do you know it is a dominant disorder? It only takes 1 copy (H)
Punnett Square for Huntington’s Disease
Write a story about this American family
with Huntington’s Disease.
Huntington’s Disease Pedigree
On the FRONT
Acquired Trait
On the BACK
Definition/characteristics: A trait or
characteristic that is developed or
learned through life. Traits you aren’t
born with. Traits GENERALLY not
controlled by DNA.
Examples:
Walking, speaking English,
dyed hair, pierced ears,
Glasses, skin cancer?
Acquired trait
Inherited trait
Sexual reproduction
Heredity
DNA
Chromosome
Gene
Allele
Genotypes
Phenotype
Dominant
Recessive
Gregor Mendel
Pea Plants
Huntington’s Disease
Punnett Square
Monohybrid cross
Homozygous (Purebred)
Heterozygous (Hybrid)
Mutation
Genetic Disorder
Sickle Cell Anemia
Hemoglobin
Pedigree
Genetics Vocabulary Flashcards due 2/28/14
Make a genetics vocabulary word chart as a study guide for your vocabulary quiz
on Friday. See some examples below. Include ALL 24 vocabulary words!
Word
Definition &
characteristics
Examples
Inherited trait
Traits that you are born
with that are passed to
you through your
parents genes.
Eye color, hair color,
widow’s peak
Homozygous
A trait where both alleles SS, tt, NN
are identical (purebred).
Genotype
Genes an organism has. Gg, SS, tt
Phenotype
Physical traits that are
observed or present
Blue eyes, sickle cell
anemia
Genetics Vocabulary Chart – Due 2/26/14
Choose ONE of the following projects to do as a summative MAJOR assessment for the
Genetics Unit. Do detailed, quality work to get full credit.
Selective Breeding vs. Genetic
Modification
Corn is one of the most
manipulated crops. Create a
Presentation or Poster
comparing traditional selective
breeding vs. genetic
modification (GMO). Explain
the two methods and then show
some specific corn
varieties/cultivars that were
created with each method and
how.
Genes associated with
inherited traits
We learned about several
common inherited human traits.
Pick at least 10 traits to research
and which genes control these
traits. Include pictures of the
traits phenotypes as part of your
presentation. You may complete
as a Word document or
presentation.
Inheritance of Eye Color
Create a Powerpoint
presentation about the genetics
of eye color. Include information
about the different types of eye
color, any genes that are
associated with eye color, and
how eye color is inherited. In
your final slide, explain how
YOU inherited your eye color.
Myths of Human Genetics
Dr. John McDonald from the
University of Delaware has
written that many of the
inherited traits students learn in
genetics class AREN’T really
inherited in a simple dominant
vs. recessive pattern that is
taught. Create a Powerpoint to
review his arguments and
compare it to what MOST
genetics students learn.
Meiosis Game
Create a game to help students
learn the steps of meiosis.
Students must answer questions
about chromosomes, genes,
DNA, and meiosis to advance
through the stages of meiosis I
and meiosis II. You win when
you reach the final gamete stage.
Plant Genetics
Grow two different species of
plants and create a digital
comparison of their phenotype
similarities and differences
(appearance, size, growth rate,
etc). Then research the genetics
of the two species summarizing
what you find. Include the
number of chromosomes and
genome size
Expanded Traits Survey
Create YOUR OWN survey of
ten inherited traits. You may use
5 of the ones we did but must
include 5 new ones. Sample at
least 50 people. Write up your
finds as a Research Investigation
Article – but with more detailed
and thorough sections than we
did as a class.
Genetic Disorders
Create a Presentation about a
specific genetic disorder. You
must include the following
information about that disorder:
description, signs/symptoms,
how it’s inherited or acquired,
genes affected (including the
mutation if known), incidence,
and treatment.
GMOs in the News
Farmers and scientists use
GMOs to create better crops.
Write a news article picking a
specific GMO and discuss the
process, the benefits, and risks
of using that GMO
History of Genetics
Create a timeline about the
history of genetic knowledge
starting with ancient times (ex.
Biblical times) through the
present. You must have at least
15 descriptions along the
timeline.
Selective Breeding in Dogs
Dog Breeders use selective
breeding to improve dog breed.
Create a brochure to explain the
selective breeding process and
use specific examples to show
how breeders have gotten new
dog breeds.
Pedigree Analysis
Create a pedigree of at least
three generations using a single
inherited trait. You must use a
REAL family either your own or
one you research. Include a
Punnett square from each
generation to show how that trait
was inherited (3 total)
Genetics Projects – due 3/21/14
Tonight…
1. Study for vocabulary quiz!
2. Complete late work!
3. Genetic project is due March 21st.
Evening Assignment