zinpro performance minerals 5r

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About Zinpro Corporation
The feed industry leader in the
manufacturing, research and
marketing of Performance
Minerals® for animals.
About Zinpro Corporation
A privately-held, family owned
company, Zinpro Corporation’s steady
growth has come as a result of:
• quality products,
• quality people and
• focus on trace mineral nutrition.
Our history
Zinpro’s history dates back to 1971,
when the late Dean Anderson
discovered how to biochemically bind
zinc to methionine to create a simple,
highly stable molecule.
This highly-stable molecule is easily
absorbed and utilized by animals.
Our history
Pioneered organic trace mineral
industry more than 45 years ago.
Continues to lead the way
with superior trace mineral
nutrition products.
Our products
• Designed and manufactured to
be the most highly absorbed
and utilized by the animal
• Zinpro manufactures products
through a patented complexing
technology
Proven research
• Our Performance Minerals are
backed by an unmatched portfolio
of science-based animal
performance data
• Research is validated and published
in peer-reviewed publications
• To date a total of 178 peer reviewed
papers published
ZINPRO PERFORMANCE MINERALS 5R
42 Peer Reviewed Publications – Poultry 1
Bahrami, A., M.M. Moeini, S.H. Ghazi and M.R. Targhibi. 2012. The effect of different levels of organic and inorganic chromium supplementation on immune function of
broiler chicken under heat-stress conditions. J. Appl. Poult. Res. 21:209-215.
Sh. Ghazi, M. Habibanm, M2.M. Moeini and A.R. Abdolmohammadi. 2011. Effects of different levels of organic and inorganic chromium and growth performance and
immunocompetence of broilers under heat stress. Biol. Trace Elem. Res. 146:309-317.
Saenmahayak, B., S.F. Bilgili, J.B. Hess and M. Singh. 2010. Live and processing performance of broiler chickens fed diets supplemented with complexed zinc. J. Appl.
Poult. Res. 19:334-340.
Moghaddam, H. N., and R. Jahanian. 2009. Immunological responses of broiler chicks can be modulated by dietary supplementation of zinc-methionine in place of
inorganic zinc sources. Asian-Aust. J. Anim. Sci. 22:396-403.
Reis, R. N., S. L. Vieira, P. C. Nascimento, J. E. Pena, R. Barros and C. A. Torres. 2009. Selenium contents of eggs from broiler breeders supplemented with sodium
selenite or zinc-L-selenium-methionine. J. Appl. Poult. Res. 18:151-157.
Chantiratikul, A., O. Chinrasri and P. Shantiratikul. 2008. Effect of sodium selenite and zinc-L-selenomethionine on performance and selenium concentrations in eggs of
laying hens. Asian-Aust. J. Anim. Sci. 21:1048-1052.
Jahanian, R., H. Nassiri Moghaddam, A. Rezaei and A. R. Haghparast. 2008. The influence of dietary zinc-methionine substitution for zinc sulfate on broiler chick
performance. J. Biol. Sci. 8:321-327.
Swiatkiewicz, S., J. Koreleski. 2008. The effect of zinc and manganese source in the diet for laying hens on eggshell and bones quality. Vet. Medicina. 53:555-563.
Barber, S. J., H. M. Parker and C. D. McDaniel. 2005. Broiler breeder semen quality as affected by trace minerals in vitro. Poultry Science 84:100-105.
Tako, E., P. Ferket and Z. Uni. 2005. Changes in chicken intestinal zinc exporter mRNA expression and small intestinal functionality following intra-amniotic zincmethionine administration. J. Nutritional Biochemistry 16:339-346.
Burrell, A. L., W. A. I. Dozier, A. Davis, M. M. Compton, M. E. Freeman, P. F. Vendrell and T. L. Ward. 2004. Responses of broilers to dietary zinc concentrations and
sources in relation to environmental implications. British Poultry Science 45:255-263.
Cheng, T., Y. Guo. 2004. Effects of Salmonella typhymurium lipopolysaccharide challenge on the performance, immune responses and zinc metabolism of laying hens
supplemented with two zinc sources. Asian-Aust. J. Amin. Sci. 17:1717-1724.
Hudson, B. P., B. D. Fairchild, J. Wilson, W. A. I. Dozier and R. J. Buhr. 2004. Breeder age and zinc source in broiler breeder hen diets on progeny characteristics at
hatching. J. Appl. Poult. Res 2004:55-64.
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ZINPRO PERFORMANCE MINERALS 5R
42 Peer Reviewed Publications – Poultry 2
Hudson, B. P., W. A. Dozier, III, J. Wilson, J. E. Sander and T. L. Ward. 2004. Reproductive performance and immune status of caged broiler breeder hens provided diets
supplemented with either inorganic or organic sources of zinc from hatching to 65 wk of age. J. Appl. Poult. Res 13 :349-359.
Hudson, B. P., W. A. I. Dozier, B. D. Fairchild, J. Wilson, J. E. Sander, and T. L. Ward. 2004. Live performance and immune responses of straight-run broilers: influence of
zinc sources in broiler breeder hen and progeny diets and ambient temperature during the broiler production period. J. Appl. Poult. Res 2004:291-301.
Virden, W. S., J. B. Yeatman, S. J. Barber, K. O. Willeford, T. L. Ward, T. M. Fakler, R. F. Wideman and M. T. Kidd. 2004. Immune system and cardiac functions of
progeny chicks from dams fed diets differing in zinc and manganese level and source. Poult. Sci 83:344-351.
Downs, K.M., R.A. Norton, K.S. Macklin, J.B. Hess. 2003. Potential of vitamin E and zinc-amino acid complex for the reduction of cellulitis in broilers. J. Appl. Poult. Sci.
23:25-32.
Dozier, W. A., III, A. J. Davis, M. E. Freeman and T. L. Ward. 2003. Early growth and environmental implications of dietary zinc and copper concentrations and sources of
broiler chicks. British Poultry Science 44:726-731.
Mabe, I., C. J. Rapp, M. M. Bain and Y. Nys. 2003. Supplementation of a corn-soybean meal diet with manganese, copper and zinc from organic or inorganic sources
improves eggshell quality in aged laying hens. 2003 Poultry Science 82:1903-1913.
Virden, W. S., J. B. Yeatman, S. J. Barber, C. D. Zumwalt, T. L. Ward, A. B. Johnson and M. T. Kidd. 2003. Hen mineral nutrition impacts progeny livability. J. Appl. Poult.
Res Vol. 12:411-416.
Chen, J. and D. Balnave. 2001. The influence of drinking water containing sodium chloride on performance and eggshell quality of a modern colored layer strain. Poultry
Science 80:91-94.
Hess, J. B., S. F. Bilgili, A. M. Parson and K. M. Downs. 2001. Influence of complexed zinc products on live performance and carcass grade of broilers. J. Appl. Anim. Res.
19:49-60.
Swiatkiewicz, S., J. Koreleski and D. Q. Zhong. 2001. The bioavailability of zinc from inorganic and organic sources in broiler chickens as affected by addition of phytase.
Journal of Animal and Feed Sciences 10:317-328.
Downs, K. M., J. B. Hess, K. S. Macklin and R. A. Norton. 2000. Dietary zinc complexes and vitamin E for reducing cellulitis incidence in broilers. J. Appl. Poultry Res.
9:319-323.
Kidd, M. T., P. R. Ferket and M. A. Qureshi. 1996. Zinc metabolism with special reference to its role in immunity. World’s Poultry Science Journal 52:309-324.
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ZINPRO PERFORMANCE MINERALS 5R
42 Peer Reviewed Publications – Poultry 3
Kidd, M. T., M. A. Qureshi, P. R. Ferket and L. N. Thomas. 1994. Blood clearance of Escherichia coli and evaluation of mononuclear-phagocytic system as influenced by
supplemental dietary zinc methionine in young turkeys. Poultry Sci. 73:1381-1389.
Pott, E. B., P. R. Henry, C. B. Ammerman, A. M. Merritt, J. B. Madison, R. D. Miles. 1994. Relative bioavailability of copper in a copper-lysine complex for chicks and
lambs. Anim. Feed Sci. & Technol. 45:193-203.
Aoyagi S. and D. H. Baker.1993. Nutritional evaluation of copper-lysine and zinc-lysine complexes for chicks. Poultry Science 72:165-71.
Kidd, M. T., N. B. Anthony and S. R. Lee. 1993. Effect of supplemental zinc in either a corn-soybean or a milo and corn-soybean meal diet on the performance of young
broiler breeders and their progeny. Poultry Science 72:1492-1499.
Kidd, M. T., N. B. Anthony, Z. Johnson and S. R. Lee. 1992. Effect of Zinc Methionine Supplementation on the Performance of Mature Broiler Breeders. J. Appl. Poultry
Res.1:207-211.
Kidd, M. T., N. B. Anthony and S. R. Lee. 1992. Progeny performance when dams and chicks are fed supplemental zinc. Poultry Science 71:1201-1206.
Wedekind, K. J., A. E. Hortin and D. H. Baker. 1992. Methodology for assessing zinc bioavailability: efficacy estimates for zinc-methionine, zinc sulfate, and zinc oxide. J.
Anim. Sci. 70:178-187.
Moreng, R. E., D. Balnave and D. Zhang. 1992. Dietary zinc methionine effect on eggshell quality of hens drinking saline water. Poultry Science 71:1163-1167.
Baker, D. H., J. Odle, M. A. Funk and T. M. Wieland. 1991. Bioavailability of copper in cupric oxide, cuprous oxide, and in copper-lysine complex. Poultry Science 70:177179.
Pimentel, J.L., M.E. Cook, and J.L. Greger. 1991. Research Note: Bioavailability of zinc-methionine for chicks. Poultry Science 70:1637-1639.
Scheideler, S. E. 1991. Interaction of dietary calcium, manganese and manganese source (Mn oxide or Mn methionine complex) on chick performance and manganese
utilization. Biological Trace Element Research 29:217-228.
Henry, P. R., C. B. Ammerman, and R. D. Miles. 1989. Relative bioavailability of manganese in a manganese-methionine complex for broiler chicks. Poultry Sci. 68:107-112.
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Zehava Uni - Research
Headquartered in Eden Prairie, Minnesota, USA
Zinpro Corporation has employees in more than 15 countries
and markets its products in more than 55 countries worldwide
Our locations
Zinpro Performance Minerals are
manufactured at the company’s
highly-specialized production
facilities located in
• Garner, Iowa (2 Facilities);
• North Branch, Minnesota
• Shell Rock, Iowa (2014)
Manufacturing assurance
Zinpro Corporation proudly participates in numerous quality
assurance certification programs including: ISO 9001:2000,
• HACCP
• FAMI-QS
• FCI
• Safe Food/Safe Feed
Why trace minerals?
Scientifically proven that trace
minerals are essential for basic
metabolic functions that affect overall
health and well-being of animals
Moderate deficiencies can adversely
impact animal performance
IMPACT OF STATUS
Impact Of Trace Mineral Status
On Biological Function
Trace Mineral Status
Decreasing Status
Increasing Status
Immunity & Enzyme Function
Maximum Production/Reproduction
NRC
Req
Normal Production/Reproduction
Deficiency
Optimal
Subclinical
Clinical
Time
Stat - 1
NRC
Req
NRC = Nutritional research council
Subclinical
Optimal
TRACE MINERAL\S INTERACTIONS
Trace Mineral Interactions
Key Interactions
Cl
P
S
K
Zn
Co
F
As
Fe
Fe
Zn
Se
Mg
Ca
Na
I
Mo
PT - 79
Cu
Mn
Ca
Cu, Ca, Fe
Zn, Cu, Mn
Zn, Cu
Trace Minerals Interactions
Effect Of Dietary Calcium On
Copper Retention
10
What about
broiler breeder diets
with 3+% Ca?
7.5
5
2.5
0
-4
0. 7
0. 8
0.9
% Ca Content of Diet
PG - 160
Adapted from Kirchgessner & Grassmann, 1970
1.0
Trace Minerals Antagonists
In Poultry Diets
 Fibers
 Myco-toxins
 Toxin binders
 Calcium (Ca)
 Clay
 Phytates
mPG - 96
(Phytic acid / antioxidant compounds found in whole grain)
45:1:5
OTMs – The “MUST’’ have Criteria
 The compound must be water soluble
 The complex must be stable in the range of
physiological pH’s (pH 2.0 to 7.4)
 The complex must be stable in presence of chelating
agents in diet
 The complex must be absorbable from the GI
 The complex must result in the increased availability of
the metal and amino acid
 The product must be proven to improve animal
performance
DIFFERENTIATION OF ORGANIC TRACE MINERALS
Organic Trace Mineral Classification / AFFCO
 Metal (Specific Amino Acid) Complex
 Metal Amino Acid Complex
Met
Zn
Zn
AA
 Metal Amino Acid Chelate
 Metal Proteinate
AA
Zn
AA
Zn
Zn
AA
AA
AA
AA
AA
AA
AA
AA
AA
Zn
Zn
 Metal Polysaccharide Complex
Zn
Zn
Zn
Zn
Zn
 Metal Propionate
CPX - 22
Zn
Zn
Zn
Zn Zn Zn
Prop.-1
Prop.-1
Zn+2
Zn
Zn
Zn
Zn
FEED
Energy
Protein
Water
Trace
Macro
Zn, Cu, Co, Mn, Cr, Se, I,
Fe
P, Mg, Na, Cl, K, Ca,
S
Other
Minerals
Oxides, Sulfates, Chlorides,
Carbonates, Selenite Acetates,
Proteinates, Glycinates ,
Propionates, Butyrates,
Polysaccharides
CG - 245
Minerals Vitamins
Fibers
Performance Minerals
ZPM