Transcript chpt12charts

Transcription Translation
Definition
Starting
Compounds
Ending
Compounds
Enzyme
Involved?
Replication
Transcription Translation Replication
Definition
To rewrite
To express
in another
language
mRNA
To copy
Ending
mRNA
Compounds
Protein/polypeptide
(sequence of amino
acids) – aided by
tRNA
2 new identical
strands of
DNA
Enzyme
Involved?
None
DNA
polymerase
Starting
DNA
Compounds
RNA
polymerase
DNA
Chromosomes,
mRNA base code
DNA code of Bases
ATT
GGG
ATA
AAA
GTA
GGG
tRNA base code
Amino acid
attached to tRNA
Chromosomes,
mRNA base code
DNA code of Bases
ATT
UAA
GGG
CCC
ATA
UAU
AAA
UUU
GTA
CAU
GGG
CCC
tRNA base code
Amino acid
attached to tRNA
Chromosomes,
mRNA base code
DNA code of Bases
tRNA base code
ATT
UAA
AUU
GGG
CCC
GGG
ATA
UAU
AUA
AAA
UUU
AAA
GTA
CAU
GUA
TAG
AUC
UAC
Amino acid
attached to tRNA
Chromosomes,
mRNA base code
DNA code of Bases
tRNA base code
Amino acid
attached to tRNA
ATT
UAA
AUU
STOP
GGG
CCC
GGG
Proline
ATA
UAU
AUA
Tyrosine
AAA
UUU
AAA
Phenylalanine
GTA
CAU
GUA
Histidine
TAG
AUC
UAC
Isoleucine
•Below are untwisted portions
of DNA. What would these
portions look like if they were
replicated? Circle the
complementary strands.
•
A-T
T-A
C-G
C-G
A-T
C-G
b.
C-G
G-C
T-A
A-T
C-G
C-G
•
Below are sequences of bases from one side of a
DNA double helix. Transcribe these sequences and
write the complimentary mRNA strand below the
DNA sequence, then translate the sequences. Write
the completed amino acid sequence below the
mRNA.
a. ATGGCTTAGGTA
b. TCCACTAACGCT
a. ATGGCTTAGGTA
b. TCCAGTAACGCT
UACCGAAUCCAU
AGGUCAUUGCGA
Tyr-Arg-Iso-Hist
Arg-Ser-Leu-Arg
Look at b. – what if it was mutated to become:
TCCAGTATCGCT , what would be the polypeptide
produced in this case?
TCCAGTATCGCT
AGGUCAUAGCGA
Arg-Ser
Using a. ATGGCTTAGGTA
• Look at the strands below and write down if a. has been
mutated by a point mutation or a frameshift mutation (if
frameshift – what type of frameshift was it?)
• 1. ATTGCTTAGGTA
• 2. ATTGGCTTAGGTA
• 3. ATGGCTTAGTA
Using a. ATGGCTTAGGTA
• Look at the strands below and write down if a. has been
mutated by a point mutation or a frameshift mutation (if
frameshift – what type of frameshift was it?)
• 1. ATTGCTTAGGTA = point
• 2. ATTGGCTTAGGTA = frameshift - insertion
• 3. ATGGCTTAGTA = frameshift - deletion