Transcript ALCOHOL

ALCOHOL
Chapter 8
PRODUCTION OF ALCOHOL
Anaerobic condition
Glucose
Pyruvate
Fermentation of yeast
CO2
Acetaldehyde
PRODUCTION OF ALCOHOL
Acetaldehyde
NADH
NAD+
Ethanol
ENERGY CONTENT OF COMMON
ALCOHOLIC BEVERAGES
Alcohol Metabolism
DIGESTION AND
ABSORPTION OF ALCOHOL
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No digestion required
Absorbed by simple
diffusion and moves directly
into blood stream
No specific mechanism
required to enter body cells
Alcohol damages cell
membrane proteins as it
enters body cells.
ALCOHOL METABOLISM
ALCOHOL METABOLISM
ALCOHOL METABOLISM
Catalase
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Found in the liver
Minor pathway for alcohol metabolism
Catalase
H2O2
Ethanol
H2 O
Acetaldehyde
What to do with Acetaldehyde?
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Acetaldehyde
dehydrogenase
Acetyl CoA is non-toxic to
body cells
Fate of Acetyl-CoA
Acetyl-CoA
CO2 + H2O
Fatty Acid
Glucose
Moderate Alcohol Consumption
Versus Alcohol Abuse
Benefits and Problems
Problems Associated with
Alcohol Abuse
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Increases 5 of the top 10
causes of death in the U.S.
Cirrhosis of the liver
Inflammation of stomach
and pancreas
Hypertension and
hemorrhagic stroke
Problems Associated with
Alcohol Abuse
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Brain damage and
neurotransmitter
imbalances
Myocardial depression
and Arrhythmias
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Cardiomyopathy
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Fetal Alcohol Syndrome