Transcript Chapter 12
Chapter 12
Dietary Supplements and
Over the Counter Drugs
© 2006 McGraw-Hill Higher Education. All rights reserved.
Dietary Supplements
Looks like a drug but not a drug
Food, Drug and Cosmetic Act
Dose vs. serving size
What they say vs. what you get
With dietary supplements, 300mg is the size
of the pill not the amount of active ingredient
Brand to brand and pill to pill ingredients
could be different
© 2006 McGraw-Hill Higher Education. All rights reserved.
Dietary Supplements
Do not have to prove effectiveness
There are seven claims they can make if the
product meets certain requirements.
DSHEA (1994)
Redefined dietary supplement
Redefined safety
“Well being”
© 2006 McGraw-Hill Higher Education. All rights reserved.
Remember…
“This statement has not been evaluated
by the Food and Drug Administration.
This product is not intended to
diagnose, treat, cure or prevent any
disease.”
© 2006 McGraw-Hill Higher Education. All rights reserved.
Saint-John’s-Wort
Hypericum perforatum
Was used to prevent possession of demons
now anxiety and depression
Can have negative interactions with
prescription drugs
© 2006 McGraw-Hill Higher Education. All rights reserved.
S-adenosyl-L-methionine (SAMe)
Active form of amino acid methionine
Researched as an antidepressant
Ginkgo Biloba
Long term use in China for medical use
Reduces blood clotting
Might improve memory
© 2006 McGraw-Hill Higher Education. All rights reserved.
Over the Counter (OTC) drugs
OTC drugs are
self-prescribed and self-administered
for
self-diagnosed illnesses
© 2006 McGraw-Hill Higher Education. All rights reserved.
OTC Label
Required label information includes:
Approved uses of the product
Detailed instructions on safe and effective use
Cautions or warnings to those at greatest risk
when taking the medication
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Psychoactive OTC
Stimulants
Weight-Control Products
Help restore mental alertness or wakefulness
NoDoz – 100 mg of caffeine
Phenylpropanolamine (PPA)
PPA and caffeine together were approved but then ruled
unsafe. In 2000 PPA was pulled
Ephedra, Benzocaine, starch blockers, Cholecystokinin,
as well as others banned.
Sedatives and Sleep Aids
Scopolamine combined with antihistamine methapyrilene
Few still available today
© 2006 McGraw-Hill Higher Education. All rights reserved.
Psychoactive OTC
Analgesics
Opioids or OTC
Scteylastes
Acetylsalicylic acid (Aspirin)
Analgesics – pain relief
Antipyretic – fever reducer
Anti-inflammatory – reduces swelling, inflammation
and soreness
Increases bleeding – inhibits blood platelet
aggregation
Reye’s syndrome
© 2006 McGraw-Hill Higher Education. All rights reserved.
Psychoactive OTC
Acetaminophen
Phenacetin and acetaminophen
Tylenol
COX enzymes
NSAIDs
Cold, Allergy and Cough Remedies
How to control the cold
Treatments for the symptoms not the cold
Chlorphenramine maleate
Dextromethorphan
© 2006 McGraw-Hill Higher Education. All rights reserved.