Transcript Abuse Deterrent Technologies: Fighting Prescription Drug Abuse

Conference of Western Attorneys
General Annual Meeting
July 20, 2015
90% of all adults with an
substance use disorder started
using under age 18
50% under the age of 15
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Medicine abuse – frightening behavior
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Some Progress to Report
The 2013 National Survey on Drug Use and Health
(NSDUH) reported:
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a 17% decline in the number of teens 12-17 initiating
“non-medical use” of prescription medication
• 125,000 fewer teens beginning this behavior versus
2012
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Challenges to Reducing Supply
• Abused medications continue to be sourced primarily
“from family and friends for free” --- i.e., from medicine
cabinets and via “sharing”
• Prescribers often not well trained in addiction medicine or
pain management, and unaware of key prevention tools
such as Prescription Drug Monitoring Programs
(PDMP’s) or Screening, Brief Intervention and Referral to
Treatment (SBIRT)
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Challenges to Reducing Supply
CDC.gov
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An Epidemic of Consequences
Drug overdose death rates continue to increase
US, 1980-2010
NCHS Data Brief, December, 2011,
Updated with 2009 and 2010 mortality data
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Prescription drugs primary driver of overdose
deaths, top 10 drug classes, US 2010
18,000
16,000
14,000
Deaths
12,000
10,000
8,000
6,000
4,000
2,000
0
Drug Class
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Jones et al Pharmaceutical overdose deaths, United States, 2010.
JAMA 2013 and CDC/NCHS NVSS MCOD 2010
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Who is overdosing?
• Every day in the United States, 44 people die as a result
of a prescription opioid overdose.
Centers for Disease Control and Prevention. National
Vital Statistics System mortality data. (2015) Available
from URL: http://www.cdc.gov/nchs/deaths.htm.
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Who is overdosing?
• Mostly white males but increases in overdose rates
across all ethnic groups between 1999-2013
• Men were more likely to die from prescription opioid
overdose, but the mortality gap between men and
women is closing.
• Deaths from prescription painkiller overdoses among women
increased more than 400% during 1999–2010, compared to
237% among men.2
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Progression to Heroin Abuse
Addiction to Rx pain relievers a precursor to heroin use:
4 out of 5 current heroin users migrated from Rx opiates
Death rates from heroin overdose are increasing rapidly as death
rates from prescription opioids are leveling off
CDC Vital Statistics
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Economic Costs
• $72.5 Billion in healthcare costs
• Opioid abusers generate, on
average, annual direct health
care costs 8.7 times higher than
nonabusers
Centers for Disease Control
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What can be done?
Policy Solutions
• Rebuild National Prevention Infrastructure
• Safe and Drug-Free Schools Program and National Youth AntiDrug Media Campaign eliminated
• Increase Use of PDMPs/SBIRT
• Prescriber Education in Rhode Island, Maryland, Delaware,
Idaho, Louisiana, Maine, West Virginia and Washington State
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Increased access to Medication Assisted Treatment
Naloxone for first responders and families
Good Samaritan Laws
Encourage development and use of Abuse Deterrent
Formulations of opiates
Medicine Abuse Project
The Medicine Abuse Project began in 2012 in response
to ONDCP’s Prescription Drug Abuse Strategy (2011),
calling for education – of parents, youth, patients and
prescribers
• Brings together 17 corporate partners (pharmaceutical industry,
chain drug stores, media), 8 federal agencies and 80+ strategic
partners
• Comprehensive website at www.medicineabuseproject.org, with
content for parents, educators, community leaders and healthcare
providers
• Main metric of performance is prevention of teen initiation of
prescription drug abuse.
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Medicine Abuse Project
“Mind Your Meds” campaign
• Recognizes that nearly two-thirds of
abused meds are sourced from family /
friends
• Encouraging responsible storage and
safe disposal
• Roughly $40 million in pro bono media
support in 2014
• Gold Lion Award at Cannes
• Directed by Eric Stoltz from Mask, Pulp
Fiction, Glee
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