Transcript Catherine Bliss PowerPoint

Racial Inclusion in Genomics
FROM BEDSIDE TO BENCH
Equality & Empowerment
Racial Inclusionary Policies
 1977 Office of Management and Budget (OMB)
Directive No. 15 mandates federal agencies to use
a standard set of race categories
 White, Black, American Indian, Asian and Pacific
Islander
 1993 National Institutes of Health (NIH)
Revitalization Act adopts OMB standards
 1998 Food and Drug Administration’s (FDA)
Demographic Rule orders OMB implementation
 2000 Strategic Plan to Eliminate Health Disparities
International Databases
 Human Genome Project (1986-2003)
 Utah, France, Venezuela
 Human Genome Diversity Project (1991-97)
 52 world populations
 Polymorphism Discovery Resource (1997-98)
 OMB
 International HapMap Project (2002- present)
 OMB inspired – Europe, Africa, Asia
 1000 Genomes Project (2005-present)
 Uses HapMap samples
Human Genome Project
 No global representation
 De-labeled
 Pooled
Human Genome Diversity
Project
 Global representation by ethnicity
 Labeled
 Classified
Polymorphism Discovery
Resource
 Global representation by OMB race
 De-labeled
 Pooled
International HapMap Project
 Global representation by continent
 Labeled
 Classified
1000 Genomes Project
Renaturalization of Race
 At the level of Global Projects
 In the central databases that supply studies
 As a point of reference for all research
Private Collections
 Serving medical and consumer needs
 Riding the fine line between race and
ethnicity
 Critical of OMB
 Trying to create opportunities for racial
belonging
Thank You!
 [email protected]