Transcript Strongyloides stercoralis

Strongyloides stercoralis
Abdirahman Gulaid
Definition
 Human parasitic disease caused by nematode
S. Stercoralis.
 Mostly in tropical, subtropical area and
temperate climate.
 Affect 30-100 million annually.
 Has two unique life cycle: Free life cycle and
Parasitic life cycle.
Definition
 Cause by direct contact with contaminated
soil and recreational activities.
 Children highly affected to bad sanitation.
 S. stercoralis is a 2 mm long intestinal worm
Rhabditiform (L1) larva of Strongyloides stercoralis is
about 0.3 mm long. (1 µm = 0.001 mm)
Life Cycle
Life Cycle
Life Cycle
Life Cycle
Pathology
 Invasive : Skin Penetration.
 Pulmonary: During Cycle or Immigration.
 Intestinal: Tissue Destruction
Symptoms and Signs of
Hyperinfection
 anemia (for example, pale skin)
 constipation
 cough
 diarrhea
 eosinophilic pneumonitis (during larvae migration through the lungs)
 Nausea
 vomiting
 weight loss.
Symptoms of Immunosuppressed patients
(organ transplant) or immunocompromised
patients (HIV):
 Death
 neurological and pulmonary complications
 shock.
Diagnosis
 Stool culture most effective way.
 Confusion diagnosis arise day-to-day variability
number of juvenile worm.
Treatment
Strongyloidiasis is treated with:
 Ivermectin.
Tthiabendazole.
 No public health strategies for controlling are active at
global level.
Control
 Good sanitation with specific care of human waste
disposal.
 Mass treatment of Ivermectin drugs shows some
progress but needs further research.
 Setting global health plan.
 Wearing permanent shoes.
 Education Program for community.
discussion
 How many people affected yearly.
 Is it one of the neglected WHO diseases.
 How many life cycle does it have.
 Where it is the main host in human body.
 What is the name of the drug treat.
 One of the best way to control.
reference
 http://www.who.int/neglected_diseases/diseases/strong
yloidiasis/en/.
 http://www.dpd.cdc.gov/dpdx/HTML/Strongyloidiasis.ht
m.
 http://www.parasite-diagnosis.ch/schistointestessentials