Szczepura and Johnson Key Papers

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Transcript Szczepura and Johnson Key Papers

NHS Evidence
Specialist Collection in Ethnicity & Health
www.library.nhs.uk/ethnicity
Clinical Leads Prof Mark Johnson & Prof Ala Szczepura
IDEA-R Workshop March 12th, 2011
NHS Evidence – provided by NICE
A search using the term ‘trial’ identifies several items of
relevance to the workshop in the SCEH collection:
Hussain-Gambles M et al.
Involving south Asian patients in clinical trials
HTA Report Oct 2004.
Summary
This 128 page report investigated how South Asian patients conceptualise the
notion of clinical trials and identified key processes that impact on trial
participation and the extent to which communication difficulties, perceptions
of risk and attitudes to authority influence these decisions.
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NHS Evidence – provided by NICE
Bartlett et al.
The causes and effects of socio-demographic exclusions from clinical
trials
HTA Report Oct 2005.
Summary
This study investigates the exclusion of women, older people and minority
ethnic groups from clinical trials. The study focuses on two drug exemplars,
statins and non-steroid anti-inflamatory drugs (NSAIDs). Literature was
reviewed on the exclusion of women, older people and minorities in
healthcare research including: clinical trials, cohorts, hospital episode
statistics and drug trials.
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NHS Evidence – provided by NICE
Hussain-Gambles M, Atkin K, Leese B.
South Asian participation in clinical trials: the views of lay people and
health professionals.
Health Policy. 2006 Jul;77(2):149-65. Epub 2005 Oct 10.
Abstract
There is little UK-based empirical research on South Asian participation in clinical trials. It
was found that lay South Asian attitudes towards clinical trial participation focused on
similarities rather than differences with the general UK population, suggesting that the
relevance of ethnicity should be kept in perspective. There was no evidence of
antipathy amongst South Asians to the concept of clinical trials, and awareness was a
correlate of social class, education and younger age. Lay factors that might affect
South Asian participation in clinical trials included: age; language, social class; feeling
of not belonging/mistrust; culture and religion. Approachable patients (of the same
gender, social class and fluent in English) tended to be 'cherry picked' to clinical trials.
This practice was justified because of a lack of time, resources and inadequate
support. South Asian patients might be systematically excluded from trials due to the
increased cost and time associated with their inclusion, particularly in relation to the
language barrier. and attitudes to authority influence these decisions.
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NHS Evidence – provided by NICE
Hussain-Gambles M.
South Asian patients’ views and experiences of clinical trial participation.
Family Practice 2004; 21: 636–642. (copy attached)
Su Mason, Mahvash Hussain-Gambles, Brenda Leese, Karl Atkin, Julia Brown
Representation of South Asian people in randomised clinical trials:
analysis of trials' data
BMJ. 2003 June 7; 326(7401): 1244–1245.
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NHS Evidence – provided by NICE