Transcript Azor

Azor
What is Azor?
Azor is a combination of
Amlodipine besylate
(am-LOE-di-peen BESS-ill-eight )
and
Olmesartan medoxomil.
(OL-me-SAR-tan me-dox-o-mil)
Components of Azor
Amlodipine besylate is a calcium
channel receptor blocker. This
part of Azor acts to “…slow the
movement of calcium across
the membranes of heart muscle
cells to slow their contraction.”
("Glossary of terms," )
C20H25ClN2O5•C6H6O3S
Components of Azor
Olmesartan medoxomil is a
Angiotensin II receptor blocker
that is “a medication that blocks
the action of angiotensin II,
permitting the blood vessels to
relax and dilate (widen), which
lowers the blood pressure”
("Definition of angiotensin," )
C29H30N6O6
Other ingredients
• “Each tablet of Azor also
contains the following
inactive ingredients: silicified
microcrystalline cellulose,
pregelatinized starch,
croscarmellose sodium, and
magnesium stearate.” ("Azor," )
Purpose
• Azor is used to treat
hypertension, also known
as high blood pressure.
• It can be used by itself or
with other medicines to
treat hypertension.
Considerations
•
“The side effects of olmesartan medoxomil are
generally rare and apparently independent of dose.
Those of amlodipine are generally dose-dependent
(mostly edema).” ("Azor," )
Edema is swelling of the body due to excess fluid.
•
“Maximum antihypertensive effects are attained within
2 weeks after a change in dose.” ("Azor," )
•
“Azor may be taken with or without food.” ("Azor," )
•
“Azor may be administered with other antihypertensive
agents.” ("Azor," )
•
“Dosage may be increased after 2 weeks. The
maximum recommended dose of Azor is 10/40 mg.” ("Azor,"
)
Drug Interactions
• “No drug interaction studies
have been conducted with
Azor and other drugs,
although studies have been
conducted with the individual
amlodipine and olmesartan
medoxomil components of
Azor, as described below, and
no significant drug
interactions have been
observed.” ("Azor," )
Dosages
• Azor pills come in four
different doses.
5/20, 5/40, 10/20 and 10/40
• The top number represents
the amount of Amlodipine
besylate and the bottom
number is the amount of
Olmesartan medoxomil.
How to use
• “Use this medication regularly to get the most
benefit from it. To help you remember, take it at
the same time each day. It is important to
continue taking this medication even if you feel
well. Most people with high blood pressure do
not feel sick. It may take up to 2 weeks before
you get the full benefit of this drug.” ("Azor oral," )
• “Do not stop taking this medication without
first consulting your doctor. Some conditions
may become worse when the drug is abruptly
stopped. Your dose may need to be gradually
decreased.” ("Azor oral," )
Precautions
• “When pregnancy is detected,
discontinue Azor as soon as
possible. When used in
pregnancy during the second
and third trimesters, drugs that
act directly on the reninangiotensin system can cause
injury and even death to the
developing fetus.” ("Azor," )
Side effects
• “Dizziness or lightheadedness
may occur as your body
adjusts to the medication.
Swelling hands/ankles/feet or
flushing may also occur.” ("Azor," )
• “To reduce the risk of dizziness
and lightheadedness, get up
slowly when rising from a
sitting or lying position.” ("Azor," )
Side effects
• “Tell your doctor immediately if any of
these rare but very serious side effects
occur: unusual change in the amount of
urine, unusual muscle pain/tenderness,
yellowing eyes/skin, dark urine, severe
stomach/abdominal pain, persistent
nausea/vomiting. “("Azor," )
• “A very serious allergic reaction to this
drug is rare. However, seek immediate
medical attention if you notice any of the
following symptoms of a serious allergic
reaction: rash, itching/swelling
(especially of the face/tongue/throat),
severe dizziness, trouble breathing.” ("Azor," )
Overdosing
• “There is no information on
overdosage with Azor in
humans.” ("Azor," )
• “But symptoms of overdose
may include: severe
dizziness, fainting, fast
heartbeat.” ("Azor oral," )
Conclusion
• Azor is an extremely safe
drug used to treat those with
a history of hypertension.
• Azor can be used by itself or
in combination with other
drugs because it has a very
low interaction rate with
other medications.
Citations
•
Heart powerpoint templates. (n.d.). Retrieved from
http://www.medicineppt.com/template/categories/anatomy/heart.
html
•
Glossary of terms. (n.d.). Retrieved from
http://www.womensheart.org/content/Help/glossary.asp
•
Definition of angiotensin ii receptor blocker. (n.d.). Retrieved
from http://www.rxlist.com/script/main/art.asp?articlekey=22558
•
Azor oral. (n.d.). Retrieved from
http://www.webmd.com/drugs/drug-149217azor+oral.aspx?drugid=149217&drugname=azor+oral
•
Medicine powerpoint templates. (n.d.). Retrieved from
http://www.medicineppt.com/template/medicine/medicineppttem
plates.html
•
amlodipine 10 mg tab . (n.d.). Retrieved from
https://members.kaiserpermanente.org/kpweb/drugency/drugdet
ails.do?drugID=235013
•
olmesartan 20 mg tab . (n.d.). Retrieved from
https://members.kaiserpermanente.org/kpweb/drugency/drugdet
ails.do?drugID=443459