Transcript Echinococcus granulosus (hydatid disease or hydatidosis)

Pulmonary hydatidosis
Dr.mohammadzadeh
Thorasic surgeon
‫اكينوكوكوس گرانولوزوس‬
‫اكينوكوكوس مولتي لوكوالريس‬
‫اكينوكوك يعني خار‬
‫هيداتيس يعني يك قطره اب‬
‫‪Echinococcus granulosus‬‬
‫كرم بالغ ‪:‬‬
‫در روده كوچك سگ شغال و‬
‫روباه زندگي مي كند‪.‬‬
‫طول ان ‪ 2/5‬الي ‪ 9‬ميليمتر‬
‫است و بدن از ‪ 3‬تا ‪ 4‬بند‬
‫تشكيل شده است‬
‫• مرحله الروي كرم به شكل كيسه اي چند جداره وپر از‬
‫مايع است كه در جدار داخلي ان جوانه هاي كيسه اي شكل‬
‫ايجاد مي شود‬
‫مرحله الروي كرم به‬
‫شكل كيسه اي چند‬
‫جداره وپر از مايع است‬
‫كه در جدار داخلي ان‬
‫جوانه هاي كيسه اي‬
‫شكل ايجاد مي شود‬
‫• طبقات مختلف كيست يك حفره اي ‪:‬‬
‫‪(1‬اليه پري سيست‬
‫‪(2‬اليه مطبق‬
‫‪(3‬اليه زاينده داخلي‬
‫‪(4‬مايع هيداتيد‬
‫‪(5‬كيسه هاي زايا‬
‫‪(6‬كيست هاي دختر‬
‫‪(7‬اسكولكس ها‬
A section of a hydatid cyst
The cyst consists
of a thick outer
layer (*), several
thinner internal
layers, and many
protoscolices.
The protoscolices
are often called
"hydatid sand."
Hydatid cyst
(Hydatid disease)
Mother cyst (left)
daughter cyst (right)
Higher magnification of the protoscolices
protoscolex.
Note the "hooks" that
will form the hooks
associated with the
adult worm's armed
rostellum.
Protoscolices with double row hooklets
Hydatid cyst
Hydatid cyst
showing a
row of brood
capsules
attached to the
germinal layer.
Egg
An egg of Echinococcus
granulosus(upper).
These eggs are virtually
indistinguishable from
other closely related
species of tapeworms
such as Taenia.
Echinococcus granulosus in the small
intestine of a dog (the small, white objects)
Although these
tapeworms are
quite small, a
single dog can be
infected with many
of them.
‫‪(1‬‬
‫‪(2‬‬
‫‪(3‬‬
‫‪(4‬‬
‫‪(5‬‬
‫‪(6‬‬
‫پنهاني بودن عالئم‬
‫خلط خوني‬
‫درد سينه‬
‫تنگي نفس‬
‫سرفه‬
‫برجستگي جدار سينه‬
‫‪Clinical Features of‬‬
‫‪unruptured cysts‬‬
Hydatid cyst in lung.
This patient had a
single large cyst in the
left lung.
An intact hydatid
cyst
An intact hydatid
cyst
Clinical Features of
ruptured cyst
i. Quiescent type
ii. Abscess type
iii. Progressive type
A patient with
bilateral
hydatid cyst
Water lily sign
Allergic reactions and sometimes anaphylactic shock
may occur if the cyst ruptures.
Ruptures of the cyst may also lead to the escape of
protoscolices into the surrounding tissues, these can
then develop into further cysts.
Differential
Diagnosis of
hydatid cyst
A
Very huge
hydatid cyst
Diagnosis
Microscopy
Fluid aspirated from a hydatid cyst will shows
multiple protoscolices (size approximately 100 µm),
each of which has typical hooklets.
The protoscolices are normally invaginated (left),
and evaginated (middle, then right) when put in
saline.
Antibody Detection
Indirect hemagglutination (IHA)
indirect fluorescent antibody (IFA) tests,
and enzyme immunoassays (EIA)
are sensitive tests for detecting antibodies
in serum of patients.
Treatment
Surgery is the most
common form of
treatment for
echinococcosis .
The drug of choice
for treatment is
albendazole .