Medication Administration
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Transcript Medication Administration
Medication Administration
Teresa V. Hurley, MSN, RN
Pharmacological Concepts
Drug Names
Chemical Name: molecular composition
Generic Name: common name
N-acetyl-para-aminophenol
acetaminophen
Trade Mark: official name, brand name
tylenol
Pharm Concepts
Classification
Effects on body system
Symptoms relieved
Desired effect
Oral hypoglycemic agents
Aspirin (analgesic, antipyretic, anti-inflammatory)
Pharm Concepts
Medication Forms: determines route
Examples
Tablets
Capsules
Elixirs
Suppositories
Regulatory Bodies
FDA (Food and Drug Administration)
enforcement of laws
State and Local (regulate tobacco and alcohol)
Health Care Institutions
Nurse Practice Acts
Pharmocokinetics
Absorbed
Administration route
Rate differs (skin, mucous membranes,
respiratory airways, GI system)
Dissolved (acidic versus base)
Blood Flow to site of administration
Body Surface Area
Lipid Solubility, with or between meals
Distribution
Circulation
Membrane Permeability
Protein Binding (free form does not bind to
albumin and is the active form of medication)
What happens in liver disease, malnurtition and
elderly?
Metabolism
Bio-tranformation (detoxify) medications
Liver main organ
Less extent lungs, kidneys, intestines
Excretion
Kidneys( main) and liver, bowel, lungs, skin
Gases and alcohol through the lungs
Medication Action
Therapeutic Effect
ASA
Analgesic
Antipyretic
Anti-inflammatory
Reduces platelet agglutination
Anti-hypertensives and Mood elevators in small
doses given for night sweats
Nitroglycerine to increase o2 supply to heart and
reduce cardiac workload
Side Effects
Adverse Effects
Minimal or serious effect
Severe response as coma
Toxic
Prolonged use, metabolism or excretion impairments lead
to build-up
Opiod Toxicity: morphine leads to respiratory depression and
death; antagonist narcon to reverse
Allergic Reactions
Medication acts as antigen
Antigen triggers release of antibodies
Mild (uriticaria; rash, pruritus, rhinitis)
Anaphylactic
constriction muscles, pharyngeal and laryngeal
edema, wheezing, SOB, hypotension,
Medic Alert Bracelet
Medication Interactions
One medication increases or lessens effect the
other
Synergistic: combined effect produces greater
effect than if given separately
Alcohol and antihistamines, antidepressants,
barbiturates and narcotics
Therapeutic Ranges
Onset: time it takes to produce a response
Peak: highest effective concentration
Trough: lowest concentration just before next
scheduled dose
Duration: concentration great enough to
produce a response
Plateau: concentration reached and
maintained after administration of fixed doses
Administration Routes
Oral Medications
PO
Buccal
Sublinguinal
Parenteral Administration (Injections)
Intradermal (ID) dermis layer
Parenteral
Subcutaneous (Sub-Q)
Tissues below the Dermis
Parenteral
Intramuscular (IM)
Parenteal
Intravenous
Topical Administration
Transdermal: 24 hours to 7 days with a
systemic effect (nitroglycerine, estrogens)
Topical provide local effects (eye, ear, nose
gtts, gargling, swabbing; rectal or vaginal
suppositories; flushing or spraying)
The Five Rights
Right Drug
Right Dose
Right Route
Right Time
Right Client
Three checks before administration
Types of Orders
Standing or Routine
Tetracycline 500 mg PO q6h
prn: when ever necessary is a subjective and
objective determination
Morphine sulfate 2 mg IV 12 hr prn for incisional
pain
Document assessment, time given, effectiveness
Order Types
Single (one time only) as pre-op or prediagnostic
Valium 10 mg PO at (9:00 am)
STAT (single dose, immediately)
Surgery Automatically cancels all of client’s
existing medication orders
New Orders Written: Transfer to another
Health Care Facility; from 1 unit to another
Distribution Systems
Must be kept under lock and key
Must be under surveillance
Stock Supply Delivery: costly and extremely
high incidence of errors
Unit Dose System: mandated by states and
regulatory agencies (NYS) and supply only
for 24 hours
Newer Technological Systems
Automated Medicine Dispensing Systems
(AMDS)
Computer control of unit doses and narcotics via
client profile
Access via nurse security code, client ID, desired
med, dosage, route from computer screen and
drawer opens, records and charges
Bar Code Scans (client and medication (name,
dosage and strength) and nurse administering
Medication Administrative Records
Check written order against the MAR
Check written order when administering IV solutions
Document all medications given on MAR
Document unusual side effects in nurses notes
Document IV solutions given on I and O sheet and in
nurses notes
Document amount of fluid given PO with
medications on the I&O sheet if client on intake and
output
Administer Medications Safely
Never recap
a needle
Place in Sharps
Container
Medication Orders
Name of Drug
Dosage
Route
Frequency
Colace 100mg PO every hs
Demerol 50 mg IM every 4 h for x
MOM 30 mL PO prn for constipation
Prevention of Errors
Check orders
Clarify illegible orders
Check B/P
Check A or A/R pulse
Check for allergies
Check lab results
Check calculations
Calculation Conversions
Not always exact between systems
60 mg = gr 1
65 mg = gr 1
ASA gr V = 300 mg
ASA gr V = 335 mg