Transcript Sleep Aids
Sleep Aids
By Jobin S. Kalathil
Sleep Orders of Interest:
Insomnia: is characterized by the inability to fall
asleep and/or remain asleep for a reasonable
amount of time.
Restless legs syndrome (RLS): is characterized by
an irresistible urge to move legs while sleeping.
Bed wetting: is associated with the involuntary
passing of urine while asleep; after the age at which
bladder control would normally be anticipated.
General Principles of Treatment:
Treatments for sleep disorders can be grouped into
three general categories:
1) behavioral/ psychotherapeutic treatments
2) medications
3) other somatic treatments (like surgery)
Insomnia
The three types of insomnia are:
1) Transient insomnia
2) Acute Insomnia
3) Chronic Insomnia
Medications:
The most commonly used drugs are:
F Benzodiazepines
Commonly prescribed
benzodiazepines
include: temazepam,
diazepam, lorazepam,
flurazepam, nitrazepam
and midazolam
http://www.etfrc.com/benzos1.htm
Non-benzodiazepine
prescription drugs
QuickTimeª and a
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are needed to see this picture.
Ambien
Lunesta
Selectively binds to the
melatonin receptors
instead of GABA
receptors.
Rozerem
Restless Leg Syndrome
Requip
http://www.neurosci.pharm.utoledo.edu/M
BC3320/images/Ropinirole.gif
Bed wetting
Two main types of drugs
prescribed:
Tricyclic antidepressant
prescription drugs (e.g.
Amitriptyline, Imipramine or
Nortriptyline)
Bed wetting
Desmopressin
Works Cited
"Cognitive Behavior Therapy and Pharmacotherapy for Insomnia."
Archives of Internal Medicine 164. 16 Mar. 2007
<http://archinte.amaassn.org/cgi/content/abstract/164/17/1888>.
Griffiths, Rr, M.w Johnson, and P.e Suess. "Ramelteon: a Novel
Hypnotic Lacking Abuse Liability and Sedative Adverse Effects."
"Mechanism of Action." Requip. 13 Mar. 2007
<http://www.requip.com/pd/hcp/mechanism_of_action.html>
Archives of General Psychiatry 63 (2006): 1149-1157. EBSCO. SMU.
12 Mar. 2007. National Institute of Health. Ambien. 12 Mar. 2007
<http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=635&type=di
splay>.
"New Drug Offers Relief From Chronic Insomnia." Cortlandt Forum 19
(2006): 22. EBSCO. SMU.
"New Evidence That the Pharmacological Effects of
Benzodiazepine Receptor Ligands Can Be Associated with
Activities At Different BZ (?) Receptor Subtypes."
Psychopharmachology. PubMed.Gov. 12 Mar. 2007.
Office of Communications and Public Liaison. National Institute
of Neurological Disorders and Stroke. Restless Legs Syndrome
Fact Sheet. 14 Feb. 2007. 12 Mar. 2007
<http://www.ninds.nih.gov/disorders/restless_legs/detail_restless
_legs.htm#84783237>.
"PRAMIPEXOLE/ROPINIROLE." National Institute of
Neurological Disorders and Stroke. 11 Mar. 2007
<http://www.ninds.nih.gov/funding/research/parkinsonsweb/drug
_summaries/pramipexole.htm>.
"Requip." GlaxoSmithKline. 11 Mar. 2007
<http://us.gsk.com/products/assets/us_requip.pdf>.
"REQUIP." http://www.requip.com/. GlaxoSmithKline. 15 Mar.
2007 <http://us.gsk.com/products/assets/us_requip.pdf>.
"Restless Legs Syndrome." Wikepedia. 14 Mar. 2007
<http://en.wikipedia.org/wiki/Restless_legs_syndrome>.
"Rozerem." Wikipedia. 10 Mar. 2007
<http://en.wikipedia.org/wiki/Rozerem>. "Sleep Disorders."
Wikipedia. 9 Mar. 2007
<http://en.wikipedia.org/wiki/Sleep_disorder>.
Wake Up