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Glomerulopathies
Bloody
mess
Dirty pipes
Fruit
medley
Glomerulopathies
Bloody
mess
Dirty pipes
Fruit
medley
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If you meet a patient with rapidly
progressive GN and alveolar
hemorrhage, suspect this
condition marked by antibodies
against type IV collagen
What is
Goodpasture’s
syndrome?
Patients with this diagnosis have
a higher risk of malignancy,
especially solid tumors; it is also
the most common cause of
nephrotic syndrome in adults
What is membranous
nephropathy?
This cause of nephrotic
syndrome is frequently
associated with HIV and heroin
use; the “collapsing” variant is
most common among African
Americans
What is focal segmental
glomerulosclerosis?
Majority with this disease,
marked by hematuria,
proteinuria and low
complement, are Hepatitis C
(+). Don’t forget to look for
palpable purpura and skin
necrosis.
What is mixed
cryoglobulinemia?
Often heralded by hematuria
1-3 days post-URI, this is the
most common cause of GN
worldwide most prevalent in
Asians and rare in blacks
What is IgA
nephropathy?
What is a
hypersegmented neutrophil?
(Megaloblastic anemia)
What are sickle cells?
(Sickle cell anemia)
What is a
Reed-Sternberg cell?
(Hodgkin’s lymphoma)
What are Howell-Jolly
bodies?
(Asplenia; hemolytic,
megaloblastic anemia)
What are hairy cells?
(Hairy cell leukemia)
A long latency of about 30-40
years occurs from exposure to
this mineral and mesothelioma
What is Asbestos?
Miners and sandblasters exposed
to this crystalline mineral are at
high risk for tuberculosis and
should have their PPD checked
What is Silica?
Coal worker’s pneumoconiosis
+
Rheumatoid arthritis
+
Multiple pulmonary nodules
What is Caplan’s
syndrome?
First described in fluorescent
lamp workers, this disease
may present with skin and
lung nodules showing
noncaseating granuloma
What is Berylliosis?
A reactive airway disease in
textile mill workers exposed to
cotton dust, it presents with
wheezing and causes “Monday
chest tightness” that improves at
the end of the work week
What is Byssinosis?
Strawberry cervix
What is Trichomonas
vaginalis infection?
Apple-core lesion
What is colon cancer?
Strawberry tongue
What is Kawasaki
disease?
(also Scarlet fever)
Cherry red spot
on macula
What is Tay-Sachs disease?
(also Central Retinal Artery
occlusion)
Watermelon stomach
What is Gastric Antral
Vascular Ectasia
(GAVE)?
Rash hour
Travel ID
Toxicology
Pick your
node
Rash hour
Travel ID
Toxicology
Pick your
node
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What is erythema migrans?
(Lyme disease)
What is pytiriasis
versicolor?
What is
dermatitis herpetiformis?
What is erythema
multiforme?
What is lichen planus?
From pulmonary to
disseminated such as in AIDS,
this mycosis can be picked up
from bird and bat droppings in
the Ohio and Mississippi River
valleys
What is
Histoplasmosis?
The most common rickettsial
infection in the US, it is
mainly transmitted by the
Dermacentor tick and is
prevalent in the Southeast such
as North Carolina
What is Rocky Mountain
Spotted Fever?
Attention: this fungal infection
that causes Valley Fever is
endemic in Arizona,
California, New Mexico and
yes, West Texas!
What is
Coccidioidomycosis?
Humans handling infected
animals, like rabbits and deer, are
accidental hosts of this zoonosis
caused by a gram-negative
bacterium common in the South
Central states, primarily Arkansas
What is Tularemia?
Let’s travel this time to the
tropics…this potentially fatal
spirochetal infection causes Weil’s
syndrome and is acquired by
exposure to the urine of infected
carrier animals such as rats
What is
Leptospirosis?
Tinnitus, vertigo, respiratory
alkalosis and high gap
metabolic acidosis…and in
kids, Reye’s syndrome
What is aspirin toxicity?
Xanthopsia, or impaired yellowgreen color perception, is a rare
but characteristic adverse effect
of toxicity from this oldest
cardiac drug
What is Digoxin?
Chronic intake of this psych drug
can cause kidney toxicity and
nephrogenic DI
What is lithium?
Myelosuppression is a well-known
hematologic adverse effect of this
MRSA-fighting drug, especially
when used longer than 2 weeks
What is linezolid?
Toxicity from this can cause high
gap acidosis, high serum osmolality
and oxalate crystals in the urine; it is
common in antifreeze
What is ethylene
glycol?
Osteoarthritic growth
of the proximal
interphalangeal joint
What is Bouchard’s
node?
Left supraclavicular
lymph node usually
suggestive of a
gastrointestinal neoplasm
What is Virchow’s or
Troisier’s node?
Tender, red, raised
lesions on the hands or feet
indicative of
subacute bacterial endocarditis
What are Osler’s nodes?
First lymph node
reached by metastasizing
cancer cells
What is sentinel
node?
Palpable metastatic node
in the umbilicus
What is Sister Mary
Joseph node?
Medical
Milestones
This Scottish Nobel Prize winner
accidentally discovered the world’s
first antibiotic named after the
fungus from where it was isolated
Who is Sir Alexander
Fleming?
Thank you for
playing