Diapositiva 1
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Transcript Diapositiva 1
www.zfbiolabs.com
BioSciencs Foro
November 8th, New York
ZF Biolabs
ZF Biolabs
ZF Biolabs is a spanish biotechnology, established in 2003
and fully devoted to R&D activities in biomedicine and
toxicology, working exclusively with zebrafish as the
selected model organism.
ZF Biolabs
Zebrafish use in Biomedical
Research
ZF Biolabs
ZF Biolabs R&D
i) Development of toxicity assays based on the use of
the zebrafish embryo (develomental toxicity,
neurotoxicity, cardiotoxicity, hepatotoxicity and short
term toxicity).
ii) Functional genomics: analysis of genes and
phenotypes in zebrafish using morpholino
oligonucleotide loss-of-function technique to study
human diseases.
iii)Development of new zebrafish supporting
technologies aimed to improve the efficiency of
embryo production.
ZF Biolabs
ZF BIOLABS COLLABORATIVE RESEARCH
PROJECTS
Partner of the EU R&D Project Nuclear envelope-linked rare
human diseases: from molecular pathophysiology towards
clinical applications” coordinated by the Medical University of
Vienna. The role of ZF Biolabs is knocking down Lamin-A gene in
zebrafish, screening for functional readouts of pathological
phenotypes, identifying molecular drug targets and screening for
new drugs.
Partner of the project “Role of FAAH in neuroprotection” in
collaboration with Univ. of Salamanca, to develop a transgenic
zebrafish model for discovering new neuroprotective drugs.
In collaboration with Canal de Isabel II, the public company in
charge of managing the water in the Madrid region, ZF Biolabs is
involved in the research project “Development of a new toxicity
assay for detecting cyanotoxins in drinkable water using
zebrafish embryos”.
ZF Biolabs
ZF Biolabs interest in USA
• ZF Biolabs is in contact with some USA Pharmaceutical
companies, which are interested in the new toxicity assays
and related zebrafish technology.
• ZF Biolabs will present its R&D results at the Health and
Environmental Sciences Institute (HESI) Workshop on
Alternative Assays For Developmental Toxicity, that will be
held on February 27-28, 2007, in Cary (North Carolina).
• According to the possibility of collaboration with US
companies ZF Biolabs will study alliances with established
US companies and/or other alternatives.