Transcript Slide 1
Inhibitor Testing in Ontario Ontario Association of Bovine Practitioners November 17, 2011 Inhibitor Testing in Ontario • • • • Background Producer Penalties Changes to Inhibitor Testing Message to Producers Roles & Responsibilities • OMAFRA • Regulatory Testing • DFO • Designated competent authority • Assess losses, costs, penalties • Ontario Dairy Council (processors) • Screen loads before unloading – All three groups involved in testing decisions Pre-November 2011 Inhibitor Testing Program • Regulatory Testing • One Bulk Tank sample / mo. • U of G. Agri-Food Lab • Load Screening • All loads tested before unloading • Rapid tests performed by processors Producer Penalties • Regulatory Testing • Screened on modified Delvo, confirmed on: Disc Assay, HPLC Sulfamethazine, LCMS-MS • $6, $9 or $12/hl penalty, shut-off for 2nd in 12 mo. • Load Screening • • • • Beta-lactams, Sulphas, Tetracylines Suspect positive loads dumped Trace back to producer samples Penalties, load costs, if producer and load samples are positive Upcoming Changes to Inhibitor Testing • Regulatory Testing • Shift to “surveillance” testing • Testing based on known or suspected risk – e.g. macrolides (Pursue) • Load Screening • Increased testing at plants by DFO & OMAFRA • Processor results confirmed using approved confirmatory (rapid) test • Increased chance of penalties, and even higher chance of assessement of losses and costs Upcoming Changes to Inhibitor Testing Approved Rapid Tests for Plants / Confirmation • Charm • ROSA 3 SL3 B-Lactam • ROSA Sulpha • ROSA Tetracycline • Idexx • SNAP B-Lactam • Plants can choose from above and may also use: – Charm SL6, IDEXX Sulfa and Tetracycline • DFO pays for tests • Screening results confirmed using same test or one of approved confirmatory tests Upcoming Changes to Inhibitor Testing Sensitivity of Approved Rapid Tests Test Kit Amoxicillin Ampicillin Cephapirin Ceftiofur Cloxacillin Pen G Charm Rosa 3 SL3 B-Lactam 6-10 6-10 12-20 60-80 6-10 3-5 IDEXX SNAP B-Lactam 4-8 4-6 11.7 5-20 50 1-4 MRL NP 10 20 100 30 6 Test Kit SMZ SDM All other sulfa's Charm Rosa Sulfa Test 2-8 0.25 - 1 1-30 Charm Rosa Tetracycline MRL 10 10 10 Oxy tetracycline Chlor tetracycline Tetracycline 50-100 50-100 10-30 100 100 100 Message to Producers – from Vets • Inhibitor testing will test for more drug families • Follow labels for withdrawal of milk and meat. • Follow prescription for withdrawal of milk and meat when using antibiotics off-label. • Have access to rapid tests for drugs used Questions? Marc Lazenby Manager, Policies & Regulatory Affairs [email protected] 905-817-2122