Transcript Substance

for the
Psychiatry Clerkship
And Now Here
Is The Host . . .
is proud
to present
Insert Name Here
The categories for today’s
Jeopardy on Substance Use
will be:
Marijuana
Nicotine
Alcohol
LSD, XTC, PCP
Inhalants
Miscellaneous
Marijuana
Nicotine
100
100
100
100
100
200
200
200
200
200
300
300
300
300
300
400
400
400
400
400
500
500
500
500
500
600
600
600
600
600
700
700
700
700
700
800
800
800
800
800
900
900
900
900
900
Alcohol
LSC, PCP,
XTC,
Inhalants
Miscellaneous
What is 4 days?
Use of a single joint can lead to a
positive urine marijuana test as
many as this number of
days later
Row 1, Col 1
What is schizophrenia?
Use of marijuana at an early age
may interact with those who have
the genetic predisposition &
promote the development of
this serious mental illness
1,2
What is anxiety/panic attacks?
The most common psychiatric adverse
side effects of marijuana use is
psychosis and this
1,3
What is memory loss?
Cognitive effects of marijuana include
amotivation, disorientation,
unsteady coordination, altered
perception, decreased consciousness
and this reason for poor academic
performance
1,4
What is 10%?
10, 20, 30, 40, 50
The percent of users who become
dependent on marijuana
is this
1,5
What is dronabinol (marinol)
This synthetic Cannabinoid agonist
is used to treat anorexia and
weight loss in AIDS pts &
nausea/vomiting in pts
getting chemo
1,6
What is anti-emetic?
Marijuana’s clinical properties
include:
anti-inflammatory effects
anti-convulsant effects
and anti- this effect
1,7
What is mild symptoms?
Potentially life threatening;
Significant discomfort;
Mild symptoms;
This most commonly describes
withdrawal from marijuana
1,8
What are amotivational syndrome?
Marijuana use that leads to a
reduction in prosocial goal
directed activities that may
contribute to poor school or
job performance is
commonly called this
1,9
What is Bupropion (Wellbutrin)?
This non-nicotine agent is thought
to increase dopamine and
norepinephrine levels and mimic
some of the effects of nicotine
2,1
What is varenicline (chantix)?
This smoking cessation medication
is a long acting partial agonist
at the α4β2NAR
2,2
What is nortriptyline?
This tricyclic antidepressant is not
first line but a second line
smoking cessation agent due to its
side effect profile
2,3
What is 21?
It is unusual to rare for an
individual to start smoking
after this age
2,4
What is day 2-3?
Nicotine withdrawal from smoking
cessation usually begins within 24
hours, and peaks at this time
after cessation
2,5
What is 2-3 weeks?
Nicotine withdrawal from smoking
cessation usually will last
this long
2,6
What is clonidine?
This alpha-2 adrenergic agonist is
used for treating hypertension but
has shown promise for
smoking cessation
2,7
What is cigarettes?
The most common tobacco use
product is this
2,8
What is tolerance?
Disappearance of nausea and
dizziness despite repeated tobacco
use is an indication of this
2,9
What is one?
For ♀ & older adults, a social or
moderate drinker is one who does
not binge drink & consumes no
more than this number of
drinks per day on average
3,1
What is opioid?
These type of peptides mediate
some of alcohol’s rewarding
effects by enhancing the
midbrain release of
dopamine
3,2
What is disulfiram (antabuse)?
This medication inhibits aldehyde
dehydrogenase leading to a build
up of acetaldehyde and negative
reinforcement of alcohol use
3,3
What is naltrexone (vivitrol)?
This medication that is used in the
treatment of alcohol dependence is
available in a monthly depot injection
3,4
What are disulfiram (anatbuse) and naltrexone (vivitrol)?
These two medications are
contraindicated in pts with
significantly compromised
liver function
3,5
What is two?
For ♂ who are < 65 y/o, a social or
moderate drinker is one who does
not binge drink &consumes no
more than this number of
drinks per day on average
3,6
What is naltrexone (vivitrol)?
This medication is an opioid mu
receptor antagonist as a
treatment option
3,7
What is acamprosate (campral)
This medication helps prevent relapse,
has a common side effect of diarrhea,
is safe in hepatic compromised pts,
but is contraindicated in pts with
severe renal disease
3,8
What are cravings?
Naltrexone is most effective in
treating this aspect of alcohol
dependence
3,9
What is inhalants?
Standard drug screens do not detect
these drugs and usage typically
declines dramatically after
the teen years
4,1
What is MDMA (ecstasy, XTC)?
The phenylalkylamines class of
hallucinogens includes mescaline,
DOM, and this most well
known drug
4,2
What is Phencylcidine (PCP)?
First developed as a anesthetic, this
drug produces feelings of separation
from mind and body-dissociation
4,3
What is MDMA (ecstacy)?
MDMA, LSD, or PCP:
Continued use of this hallucinogen has
been linked to neurotoxic effects
4,4
What is cardiac arrhythmia?
Any inhaled volatile hydrocarbons
(glues, fuels, paints) may produce
“sudden sniffing death” due to this
4,5
What is 8?
Phencylclidine (PCP) can be
detected in the urine up to this
many days after use
4,6
What is lysergic acid diethylamide (LSD)?
The ergoline class of hallucinogens
includes this drug which often
produces visual hallucinations
which can be frightening to the use
4,7
What are inhalants?
While lab testing can detect PCP, may
or may not be helpful detecting
hallucinogens, lab testing is not
helpful detecting this
4,8
What is Phencyclidine (PCP)?
Intoxication with this drug may
produce vertical or horizontal
nystagmus, diminished
responsiveness to pain, and
violent behavior
4,9
What is nicotine?
The proportion of users of this are
most likely to become dependent
on the substance
5,1
What is cocaine?
Use of this illicit drug is most
commonly involved in ER visits
5,2
What are hallucinogens?
(Primarily LSD)
When sober, users of this drug(s)
may re-experience geometric
visual hallucinations, flashes of
color, intensified colors, or
misperception of objects being
too large or too small
5,3
What is anxiety?
About 50% of people who attempt to
quit smoking develop withdrawal
and commonly complain of
irritability, difficulty
concentrating, and this
5,4
What are 1 in 20 (5%)?
Over 80% of tobacco users attempt to
quit, 60% relapse within 1 week,
and this number succeed and
do not ever relapse
5,5
What are 12?
A drink is defined as a 1.5 ounce shot,
this 4-6 ounces of wine, or this many
ounces of beer
5,6
What are hallucinations?
And paranoia
Psychostimulants specifically worsen
this symptom of schizophrenia
5,7
What is nicotine?
Use of marijuana, alcohol, or this
before age 15 are considered to be
the three “Gateway Drugs” to later
dependence problems
5,8
What is marijuana?
The most common illicit drug used
worldwide across all age
groups is this
5,9