Transcript Presentation - Sage Bionetworks

Gustavo Stolovitzky, Chair
Alex Pico, Barry Demchak, Trey Ideker
Andrea Califano, Chair
Christina Leslie, Lonnie Welch, Chairs
Manolis Kellis, Chair
Steven Leard, Chris Williams
 13 Keynote Speakers
 63 Oral communications
 152 Posters
 4 Workshops (2 Cytoscape + 2 DREAM)
 DREAM: 368 challenge submissions
Great demand from colleagues wishing to share their data challenges
led us to organize winter (n+0.5) and spring challenges (n+1)
8.5 + 9
A Dialogue on Reverse Engineering Assessment
and Methods
DREAM was a component of several grants funded in 2014
U54 NIH LINCS Program:
• Harvard Medical School: Pharmaco Response Signatures and Disease
Mechanism
• OHSU: Extrinsic Perturbations of Cell Physiology and Associated
Regulatory Networks
U54 DCIC:
• ISMMS: Data Coordination and Integration Center for LINCS-BD2K
Canada NSERC
• Cancer Genome Collaboratory (the Somatic Mutation Challenges)
R21:
• Univ of Notre Dame: Transcript networks and crowdsourcing to
predict drug combinations in malaria parasites
And we are also involved in several other submitted grants
• We organized the first DREAM Hackathon for the
AML Challenge at Rice University
• Organized over 15 Webinars
• Two community phases following the competitive
phase
DREAM 8.5 and 9 exceeded
previous participation
Number of Submitting Teams
400
350
300
250
200
150
100
50
0
DREAM Participation
Challenges
DREAM 8.5 + 9
SMC
Registered
Users
360
Leader
board
1094
Forum
Entries
120
Unique
Submissions
173
Unique
Teams
50
RA
369
4914
52
32
21
AD
520
1972
80
43
24
AML
231
583
184
72
42
GEP
300
2896
233
48
22
Total
1780
11459
669
368
159
Our association has led to a very productive year
Feb 2013
SYNAPSE IS ENHANCING ITS CHALLENGE
HOSTING CAPABILITYIES
Come to the Workshop Tuesday at 6:45PM (pizza & drinks on us)
Synapse: collaborative platform for DREAM Challenges and
much more

http://dreamchallenges.org/
2014 DREAM PUBLICATIONS
NCI - DREAM Drug Sensitivity Prediction Challenge (Jun 2014)
NCI - DREAM Drug Synergy Prediction Challenge (Dec 2014)
2014 DREAM PUBLICATIONS
DREAM 7 - ALS Progression Prediction Challenge (Nov 2014)
DREAM6+7: Net Inf & Param Estimation Challenge (Feb 2014)
2014 DREAM PUBLICATIONS
We are organizing several Challenges that we will discuss later
today (more info in dreamchallenges.org)
DREAM 9.5 (this winter)
 ICGC-TCGA DREAM SMC Challenges: RNA and heterogeneity
 DREAM Olfaction prediction Challenge
 Prostate Cancer Challenge
DREAM10 (work in progress, next spring)
 ALS Stratification Challenge (Indiegogo campaign)
 Drug Synergy Prediction Challenge
 Digital Mammography Challenge
Thanks: Conference Sponsors
and Journals
Challenge
Organizers
Too many thanks to express…
The 159 teams that participated
and
Thea Norman!
• There is a crew making a short video on
DREAM. Let us know if you don’t want to appear
in it.
• There is a board for posting information, jobs,
etc. Take a look (I am looking for a post-doc).
• There will be a workshop at 6:00PM today, and
another at 6:45PM tomorrow. Please write your
name in the sheets that are going around to
know how many pizzas and beer to order!