Transcript Mechanism
Chapter 10 Reactions of Alcohols, Amines, Ethers, Epoxides, and Sulfur-Containing Compounds Fill in the Box with Reaction Conditions or Product Do not confuse SN2 reactions for a German SN2 which was used as a radar system in WWII The Artificial Sweetener Splenda (Sucralose) Could Splenda be a cellular alkylating agent? No, it is too polar to enter a cell. Provide Correct Reagent/Reactant/Product Provide Correct Reagent/Reactant/Product Meep-Meep is trying to perform and E1 reaction but has come up with a strange and unexpected product. Give a mechanism to explain his reaction. Mechanism: Meep-Meep Chromium Oxidation Mechanism (via Chromic Acid) Na2CrO7 – Precursor to H2CrO4 Mechanism: CrO3 – Precursor to H2CrO4 PCC – Mild Oxidant List all potential reagents used for oxidation and if a ketone, aldehyde or carboxylic acid is generated. Benzoic Acid is used As a preservative to prevent against bacterial and fungal growth. It’s added to many drinks including Diet Coke. Quinone functional group used in the living organisms to perform oxidations with in cell. So your body also does oxidations as we speak. Citral is produced by lemons naturally and smells like lemon peels. Used in the perfume industry to make nice smelling oils. Bodies Natural Oxidation: Alcohol Dehydrogenase Too much ethanol In system effects the nervous system and results in becoming “drunk” The headache of a “hangover” is the result of too much of toxic acetaldehyde in ones system. Human Liver contains both Alcohol and Aldehyde Dehydrogenase Alcohol dehydrogenase Aldehyde dehydrogenase For Each of the Below: Indicate Reaction Condition and Predict the Product Acid monster from the 50’s Smoking and Cancer Not all smokers get cancer Benzopyrenes in chimneys were responsible for cancer of the scrotum in “chimneyboys.” The connection between cancer and chimney soot was made by Percivall Pott in 1775. 11 Arene oxides as a carcinogen: DNA backbone 12 Benzene is also a Carcinogen Before the discovery of the health hazards of benezene, mechanics would routenely wash object with benezene including their hands! Predict the Product for Each Reaction The nasty smell of a dirty trash can or rotting meat is attributed mostly to amines and sulfur containing molecules. As you now know, these molecules are great at SN2 Nu’s and can do reactions in your body! Your nose is likely warning you of that! This product gives the smell of garlic … you could make it in lab.