Transcript Glaukos

Mr. A. Waldock MD BMed Sci (Hons) BM BS FRCOphth
Consultant Ophthalmic Surgeon
Ophthalmology Training Programme Director,
East of England Deanery
Glaucoma
• Glaucoma thought to derive from the ancient Greek
word… Glaukos… To glow or shine; blue-green; owl
• “Glaucosis” first documented by ancient Greeks in
400BC as a “blinding disease occurring most
commonly in the elderly”
“A group of diseases that have as a common end point
a characteristic optic neuropathy which is
determined by both structural change and
functional deficit”
Classic glaucomatous optic neuropathy
Classic glaucomatous visual functional deficit
The Dilemma with Glaucoma
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Asymptomatic
“Screening” by optometrists highlights “glaucoma”
due to RAISED intra-ocular pressure (IOP)
Prevalence of OAG in the UK estimated 1.2%
In L&D catchment area, ~ 4000 patients
Glaucoma <30% Eye Dept workload
Diagnosing earlier and living longer
Management of Glaucoma
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Multidisciplinary approach
Provide high quality diagnostic service
Provide comprehensive treatment service offering:A) Complete range of medications (eyedrops)
B) Several laser treatments
C) Modern glaucoma filtration surgery
Multiple audits over last 10 years illustrate
outcomes better than National Standard
Early Diagnosis and
Accurate Monitoring of Glaucoma
Digital Imaging of Optic Nerve Head (ONH)
3-dimensional image illustrating ONH shape
Quantitative Analysis of Optic Nerve Head
Structural Change Analysis of Optic Nerve Head
Modern Laser Treatment
for Mild Glaucoma
Selective Laser Trabeculoplasty (SLT)
SLT Audit / Outcomes
• Preliminary audit to confirm safety and efficacy
• Mean lowering of IOP = 4mmHg (20%)
• Range from 0% to 60% lowering of IOP from pretreatment values
• 2:5 eyes had a >20% IOP lowering effect
• 1:7 non-responders
• 3% transient intra-ocular inflammation post-laser
• Summary: SLT is safe and effective
Definitive Modern Glaucoma Filtration
Surgery for eyes not reaching target
intra-ocular pressures
0.01mg/ml Mitomycin C trabeculectomy
MMC Trabeculectomy Audit / Outcomes
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5 year follow up MMC Trabeculectomy outcomes
IOP is lowered by 12mmHg (46%) at 5 years
30% no eyedrops at 5 years, rest on 1 medication
Equates to a 91% success rate at 5 years
25% develop mild cataract, may require surgery
MMC Trabeculectomy is safe & effective
Combined MMC Phaco-Trabeculectomy
Audit / Outcomes
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2 year follow up MMC Phaco-Trabeculectomy
IOP is lowered by 10mmHg (45%) at 2 years
80% no eyedrops at 2 years, rest on 1 medication
47% demonstrate improvement in visual function
Equates to a 85% success rate at 2 years
MMC Phaco-Trabeculectomy is safe & effective
Cyclodiode Laser Treatment
for Advanced Glaucoma
and Painful Blind Eyes
Cyclodiode laser for advanced glaucoma
Cyclodiode Laser Audit / Outcomes
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Mean lowering of IOP = 8mmHg (28%)
3:4 eyes greater than 20% IOP lowering effect
50% required only single treatment session
3:5 painful eyes comfortable after one treatment
60% reduced eyedrops by 2 or more medications
8% complication rate (inflammation; loss of vision)
Summary: Cyclodiode laser is safe and effective
The Glaucoma Time Plot
Aim of the glaucoma specialist:
Full
Not to manage blindness
Preserve vision throughout life
Do no harm!
Patient
diagnosed
with glaucoma
Visual
Function
Significant visual
impairment
Nil
Birth
Age
100 yrs
Thank you for your attention