Transcript VICTR Data Management

VICTR Data Management
CRC Research Skills Workshop
Michael Assink
April 6th, 2012
VICTR – CTSA at Vanderbilt
• The Vanderbilt Institute for Clinical and
Translational Research (VICTR) is supported by
the Vanderbilt Office of Research and the NIH
sponsored Clinical and Translational Science
Award (CTSA)
• Mission: transform the way ideas and
discoveries make their way into patient care
VICTR Data Management
• Synthetic Derivative
– De-identified database and tools, well-established
• Research Derivative
– Fully identified clinical database, specialized for
research, new and still under development
• [ BioVU ]
– DNA Databank – uses Synthetic Derivative for
analysis
• REDCap (integration)
Synthetic Derivative (SD)
• Indexed by a one-way hash of MRN
• Notes are scrubbed of names, dates are
shifted
• Front-end tool typically used for access and
analysis
• Services are available to help deliver results
for non-standard queries (temporal queries,
controls matching, etc)
Research Derivative (RD)
• Fully identified repository of integrated clinical data
• Integrates many data sources across the enterprise –
EDW, HEO, StarPanel to name a few
• Available exclusively for IRB-approved studies
• User front-end is still under development
• Some REDCap integration (labs), Recruitment Tool
development underway
• All other results are delivered by analysts on a fee-forservice basis (work <= ~1 hour can be covered by our
CTSA infrastructure grant)
Types of Requests Suited to the RD
• Any study requiring identifiable information
• Studies needing manual review (necessitating
use of MRNs in StarPanel)
• Situations where cohorts or other identified
data already exist, and need to be matched to
other variables
• Time-sensitive requests (recruitment)
• Specialized data sets not available in SD
RD Datasets
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Codes – ICD9 & CPT4
Demographics, encounters
Lab results
Medications (Wiz, RxStar, PAML, others)
Star documents (reports, etc.)– indexed
Registries – Tumor, Cardiology (STS/ACC)
Star Forms, some flowsheets
RD Request Steps
• Research Data Request Form
• IRB application if needed, or simple
verification if already in place
• Population definition
• Variable (extract) definition
• Rinse and repeat
Leveraging VICTR Resources
• Record Counter (RC) – part of SD but open to
anyone with a Vunet ID:
https://biovu.vanderbilt.edu/RC/RC.html
• SD – see slides in other presentation (next)
• RD – email or call me, or fill out a Request
form at https://starbrite.vanderbilt.edu/
• (https://starbrite.vanderbilt.edu/managedata/
datarequest.html )