When the castle walls have been breached: The Immune System

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Transcript When the castle walls have been breached: The Immune System

5/5 Daily Catalyst Pg. 67 Immune System
 1. I have West Nile Virus. I got the virus from a mosquito. Is this
an example of a communicable or non-communicable disease
and WHY?
 2. Taking daily multi-vitamins to improve bone health is an
example of (cause, symptom, treatment, or prevention)?
 3. Describe why seeing blood in your urine is a sign of kidney
disease/damage?
5/5 Class Business Pg. 67 Immune System
 Public health campaign presentations
 Human body test on Thursday
 See me for tutoring
 Review day on Wednesday
 Extra credit: gloves, paper towels, hand sanitizer, tissues, band
aids, pens, pencils, paper, red pens, tape, glue, and colored
paper, markers, and, white board markers
 Extra credit school play
 May 1, 2, 9
 ½ sheet review STAPLED to your ticket
 All make up work is due Monday, May 11th
Data
 Grade danger list: Camila, Tashtoni, Estephanie,
Lavone, joseph, Mohammad, Hannah L., and Chris
Grade breakdown
Number of students
A
1
B
11
C
8
D
3
5/5 Agenda Pg. 67 Immune System
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Daily Catalyst
Class Business
Objective
Presentations
Immune System notes
Practice time
 Present
5/5 Objective
Today, we will compare the
functions of the basic components
of the human immune system and
determine the relationship
between vaccination and immunity.
Lesson Starter
Some diseases are communicable and can be transferred directly or
indirectly from host to host. Other diseases are non-communicable.
Which disease listed in the table is non-communicable?
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A) shingles
B) impetigo
C) hemophilia
D) ringworm
Immune System
 Turn and Talk with your classmates:
 On Thursday, we talked about the fact that patients
do not usually die of HIV/AIDS. They can die of
something as small as a common cold. Explain why
this is true.
 HIV/AIDS (virus) attacks the immune system’s white
blood cells and the body cannot fight off invaders,
like the common cold.
This unit is about maintaining
homeostasis in the human body!
Homeostasis:
You want to
be like this on
the inside…
Even if the
outside world is
like this…
One of the main ways to disturb
homeostasis is disease!
Did you know: Researchers from the Wright Patterson Medical Center in
Dayton, Ohio, asked people standing in line at a grocery store checkout and at
a high school concession stand to trade a $1 bill from their pocket for a new
one. Then the doctors analyzed 68 of those old, worn bills.
87% of these bills contained harmful
bacteria that could cause illness!
Ewwwww
Essential questions:
1.What does my body do when a pathogen
invades my body?
2.Why am I not always sick if I come in contact
with pathogens often?
Function of the immune system:
Key Point #1: FunctionFight off infection by keeping pathogens OUTSIDE the body
and killing pathogens if they invade the body
The army
of the
body!
Pathogens-review!
1. BACTERIA
2. VIRUSES
3. FUNGI
Pathogens cause
disease!
Key Point #1: Fight off infection by keeping pathogens
OUTSIDE the body
Key point #2:
1st LINE OF DEFENSE
1.The skin
2.Mucous membranes
3.Stomach acid
WAIT!!!
What if the pathogen gets past your first line of
defense and breaks into your body???
Key Point #1: Fight off infection by keeping pathogens
OUTSIDE the body and killing pathogens if they
invade the body
Key Point #3:
2nd second line of defense
 Inflammatory response
EVER
F________
WELLING
S____________
EDNESS
R________
H________
EAT
If the body’s first and second lines of
defense don’t work then the immune system
must identify and kill the pathogen.
 Key point #4:
 3rd line of defense
 White blood cells
 B Cells
 T Cells
 “Army”
 Key Point #5: Every pathogen has a unique
fingerprint called an antigen.
Pathogen
Pathogen
Pathogen
Step 1- Investigate the problem
Step 1:
 B-cells bring antibodies that
bind to the antigen
 Antibodies are flags
Antibody
binding to
antigen
Step 2- Call for back-up!
 Step 2:
 Antibodies signal white blood cells to fight the
pathogen
Step 3- Arrest the criminal!
Step 3:
T cells break down the
pathogens and destroy
them
Step 4- Put them in the system
• Step 4:
Memory b-cells memorizes the pathogen
• Antibodies will be immediately released
Vaccines
Key Point #6:
 Vaccines contain weakened or dead versions of the pathogens.
 Your body releases antibodies in case it sees the pathogen
again.
Vaccines DO get your body to produce the
antibodies for the pathogen so if you do get sick,
you can fight it off easily!
Propose an explanation for we see
measles steadily decline after 1965.
 Stop and Jot
For Class Points…
1. Which of the following is a part of your body’s first
line of defense against pathogens?
a. White blood cells
b.Red blood cells
c. Skin
d.Nervous system
 2. A pathogen is…
A) Pathway for white blood cells to follow to attack
diseases
B) A disease causing agent such as a virus or bacterial
infection
C) The best medicine for bacterial infections
D) A cell that matches up to an antigen
3. Which of the following is not part of your body’s
immune system:
a)Stomach
b)White blood cells
c)Skin
d)antibodies
4. What part of your immune system can be compared
to a SWAT team because it surrounds and destroys
pathogens?
a) Skin
b) White blood cells
c) antigens
d) antibodies
5. Memory B-cells…
a) Help your body remember the part of your body that was last
infected
b) Show your body how to fight all infections with the help of your
brain
c) Form after the pathogen has been fought off to help form
antibodies in the future
d) Remember the type of white blood cell that needs to be used to
fight a certain disease
C, form after a pathogen has
been fought off
By the end of today you will be able to
answer the questions:
1.Why am I not always sick if I come in
contact with bacteria that often?
2.What does my body do when I do get
sick?
Work Time
 Directions: Using your notes, work with your partner to
complete the immune system assignment. When you are
finished, begin reviewing for the exit ticket and working on test
corrections.
 Time: 15 minutes
 Noise: 1 (with partner)
Exit ticket #15
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 Name: __________ Period: 2 Date: 4/29 Score: _____/4
1. Who is the “army” of the immune system?
2. While you were building a real life model of DNA, you cut your
arm. The cut on your arm starts to swell and turns red. What line of
defense has been activated?
3. Why will the doctors check your white blood cell count if you are
sick?
4. Describe how vaccines work.