Transcript Immunity

Immunity
Your body’s defense
against infection!
Immune System
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A group of organs and
tissues that protect you
from foreign invaders
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Skin
Thymus gland
Bone marrow
Spleen
Lymph nodes
White blood cells
Antibodies
Passive Immunity (innate
immunity)
Structures that are there already
(because of your genes) that
protect you from foreign invaders
SKIN
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Physical barrier against
invasion
Epidermis- layer of
dead skin cells
constantly replaced by
cells underneath
Oils and sweat acidify
surface, contain
enzymes that digest
bacteria
Stomach acid
Hydrochloric acid
Hydrochloric
acid of
and enzymes
stomach
has bacteria
a pH ofthat
1destroy
2= kills
bacteria
youmost
swallow
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that you swallow
Stomach also has
enzymes that destroy
bacteria
H. Pylori bacteria burrow into
the mucus layer to avoid the
acid- can break thru stomach
wall and cause ulcers
Eyes
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Tear glands
produce tears
that bathe surface
of eye
Enzyme called
lysozyme destroys
bacteria
Ears
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Wax traps
bacteria and
viruses
Ear drum forms
a complete
barrier across
the ear canal
Nose
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Hairs trap foreign
particles
Mucus layer also
traps things, then
they are either
sneezed out or
swallowed
Respiratory Tract
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Cells lining
respiratory tract
have CILIA- tiny
hair-like structures
that beat in unison
to push foreign
particles back up to
the back of your
throat, where they
are swallowed
Respiratory epithelium: 1-cilia; 2-mucus cell
Urinary/Reproductive Tracts
Vagina is slightly acidic,
contains mucus
 Urethra is also acidic
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Temperature
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Your body PURPOSELY elevates its
temperature when you have an
infection.
Bacteria can only live at certain
temperatures, so hopefully the elevated
body temperature will kill them.
So what happens if a foreign invader
makes its way into your body???
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Blood clottingstops up wounds in
blood vessels, also
helps prevent
infectious agents
from getting in
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Platelets block
wound
Fibrin protein forms
scab
Fibrin protein (green
stuff)
ACTIVE IMMUNITY
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Your body’s acquired immune system
Triggered by a specific attack by a
specific pathogen
Also called immune response
White blood cells- key players in
immune response
White blood cells can:
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Engulf and destroy pathogen
Produce antibodies that destroy
pathogens
Produce antitoxins that neutralize toxins
made by pathogens
White blood cell
engulfing
bacteria (what
shape are these
bacteria?)
White blood cells
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Recognize marker
proteins on the
surface of cells as
our own (self) or
foreign (nonself)
These foreign
markers are called
ANTIGENS
Lymphocytes: T cells and B
cells
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Produce antibodies
against specific
pathogens