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http://r2d2.dnalc.org/media/a/sickle_cell_big.swf
http://www.ygyh.org/sickle/causeb.htm
http://www.rcsb.org/pdb/molecules/pdb41_2.html
http://www.ygyh.org/sickle/have02.htm
http://www.ygyh.org/sickle/have03.htm
http://www.ygyh.org/sickle/have07.htm
Geographic Distribution of Hemoglobin S
Geographic Distribution of Malaria
Malaria
Caused by protozoa of the Plasmodium genus.
Overlap of malaria endemic areas (Plasmodium
falciparum) and areas where sickle cell mutation
occurs.
Sickle cell mutation confers protection from
Plasmodium falciparum.
Anopheles mosquito
Malaria infects 300 to 500 million people worldwide and accounts
for over 1 million deaths annually.