Transcript Document

Chapter 19
Fighting Disease
Section 1: Infectious Disease
 Objectives:
 Explain the cause of infectious disease and identify the
kinds of organisms that cause disease
 Describe methods in which pathogens enter the body
Disease and Pathogens
 Organisms that cause disease = pathogens
 A disease that can pass from one organism to another
= infectious disease
 Infectious diseases are caused by pathogens
Disease and Pathogens
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4 major groups of human pathogens:
1.
2.
3.
4.
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Bacteria
Viruses
Fungi
Protists
Each infectious disease is caused by a specific
pathogen
Disease and Pathogens
 Examples:
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Bacteria causes strep throat
Viruses cause the flu
Fungus causes athlete’s foot
A protist causes malaria
Disease and Pathogens
 In 1860’s Louis Pasteur showed microorganisms
cause certain diseases
 Pasteur developed a method of heating foods to
kill microorganisms = pasteurization
 Influenced British surgeon Joseph Lister to
sterilize his hands and instruments before
surgery AND
 After surgery to cover wounds with treated
bandages
Surgery in the 1800’s
Modern Surgery
How Diseases are Spread

You can become infected by a pathogen in one of
several ways:
1.
2.
3.
4.
By another person
By contaminated objects
An animal bite
The environment
Person to Person Transfer
 Direct physical contact:
 Kissing
 Hugging
 Shaking hands
 Indirect contact:
 Sneezing
 Coughing
Contaminated Objects

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Food
Water
Towels
Silverware
Stepping on contaminated nails
Animal Bites
 Rabies
 Lyme disease
 Rocky Mountain spotted fever
Pathogens from the Environment
 The bacteria that causes tetanus lives in soil and
water
 The bacteria that causes botulism lives in soil
Section 2: The Body’s Defenses
 Objectives:
 Identify the body's barriers against pathogens
 Describe the role of the inflammatory response in
fighting disease
 State how the immune system responds to pathogens.
 Describe HIV and list the ways it can be spread
Barriers That Keep Pathogens Out
 Barriers such as the skin, breathing passages, mouth,
and stomach trap and kill most pathogens with which
you come into contact
The Skin

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Chemicals in oil and sweat can kill pathogens
Pathogens can fall off with dead skin
Washing with soap and water decreases pathogens
Scabs over cuts prevent pathogens from entering the
body
The Breathing Passages
 Mucus and cilia in the nose, pharynx, and bronchii
trap and remove pathogens that enter the respiratory
system
 Sneezing and coughing force pathogens out of your
body
The Mouth and Stomach
 Saliva and stomach acid kill most pathogens that you
swallow
General Defenses
 In the inflammatory response, fluid and certain types
of white blood cells leak from blood vessels into
nearby tissues.
 The white blood cells then fight the pathogens
 White blood cell that engulfs and destroys pathogens
= phagocyte
The Immune System
 The cells of the immune system can distinguish
between different kinds of pathogens.
 The immune system cells react to each kind of
pathogen with a defense targeted specifically at that
pathogen
 White blood cells that recognize pathogens =
lymphocytes
T Cells
 Distinguish between different kinds of pathogens
 Molecules on cells the immune system recognizes as
either part of your body or outside your body =
antigens
B Cells
 Produce chemicals that help destroy pathogens
 Chemicals are called antibodies
 Each B cell produces only 1 specific antibody
AIDS, a Disease of the Immune System
 AIDS = a disease caused by a virus that attacks the
immune system
 Caused by the HIV virus
 Attacks and destroys T cells
Section 3:
Preventing Infectious Disease
 Objectives:
 Define and explain active immunity
 Define and explain passive immunity
 Identify some strategies for staying healthy
Active Immunity
 The body’s ability to destroy pathogens before they
can cause disease = immunity
 When a person’s own immune system produces
antibodies in response to the presence of a pathogen
= active immunity
How Active Immunity is Produced
 T cells and B cells remember the antigens they come
into contact with
 When they encounter that antigen again the immune
response is very quick and you usually don't get sick
Vaccination
 The process by which harmless antigens are
deliberately introduced into a person’s body to
produce active immunity = vaccination
 The substance used in the vaccination = vaccine
 Usually contains dead or weakened forms of the
pathogen
Passive Immunity
 When a person is given the antibodies = passive
immunity
 Occurs when the antibodies that fight the pathogen
come from another source rather than from the
person’s own body
Staying Healthy
 Don’t share items that might carry pathogens like
toothbrushes, drinking straws, and silverware
 Wash hands before eating and after using the bathroom
 Cover your mouth when sneezing and coughing
 Get 8 hours of sleep every night
 Eat a well-balanced diet
 Get regular exercise
Section 4: Noninfectious Disease
 Define an allergy
 Explain how diabetes affects the body
 Explain how cancer affects the body
What are Noninfectious Diseases?
 Noninfectious disease –
diseases not spread
from person to person
 Not caused by
microorganisms
Allergies
 Allergies – disorder in which the
immune system is overly sensitive
to a foreign substance
 Allergen – any substance that
causes an allergy
 Histamine – chemical that is
responsible for the symptoms of an
allergy
Asthma
 Asthma – disorder in
which the respiratory
passages narrow
significantly
 Short of breath
 Brought on by stress,
exercise, allergies
Diabetes
 Diabetes – a condition where pancreas fails to
produce insulin or body cells can’t use it properly
 Insulin – a chemical that allows body cells to take
in glucose from blood
 Person excretes glucose in urine
 Body cells do not have enough glucose for energy
Insulin Pump
Effects of Diabetes
 Lose weight
 Weak
 Hungry
 Urinate frequently
 Feel thirsty
 Long-term effects
Two Forms of Diabetes
 Type I
 More serious
 Begins in childhood
 Type II
 Develops during adulthood
 May not need to take insulin
Cancer
 Cancer – disease in which
cells divide uncontrollably
 Tumors – abnormal tissue
masses
 Often caused by carcinogens
– a substance or a factor in
the environment that can
cause cancer