Transcript Slide 1

Why do we test?
 1.
We want to prevent an outbreak of Tuberculosis in
our campus community
 2. We want to find those that are affected and get
them treated so you are able to continue to participate
in your schooling.
Tuberculosis
 What is it?
 Tuberculosis (TB) is a disease caused by germs that are
spread from person to person through the air. TB usually
affects the lungs, but it can also affect other parts of the
body, such as the brain, the kidneys, or the spine. A
person with TB can die if they do not get treatment.
 About 10-20% of the international students that we
screen each semester will be positive for a tuberculosis
infection and will need further work up!
Tuberculosis Continued
 How is it spread?
 TB germs are put into the air when a person with TB
disease of the lungs or throat coughs, sneezes, speaks, or
sings. These germs can stay in the air for several hours,
depending on the environment. Persons who breathe in
the air containing these TB germs can become infected;
this is called latent TB infection.
 http://www.cdc.gov/tb/
Active versus Latent Disease
The Difference between Latent TB Infection and TB Disease
A Person with Latent TB Infection
A Person with TB Disease
• Has no symptoms
• Has symptoms that may include:
- a bad cough that lasts 3
weeks or longer
- pain in the chest
- coughing up blood or sputum
- weakness or fatigue
- weight loss
- no appetite
- chills
- fever
- sweating at night
• Does not feel sick
• Usually feels sick
• Cannot spread TB bacteria to others
• May spread TB bacteria to others
• Usually has a skin test or blood test
result indicating TB infection
• Usually has a skin test or blood test result indicating TB
infection
• Has a normal chest x-ray and a negative
sputum smear
• May have an abnormal chest x-ray, or positive sputum
smear or culture
• Needs treatment for latent TB infection to
prevent active TB disease
• Needs treatment to treat active TB disease
QFT
 What is it?
 The QuantiFERON®-TB Gold test (QFT-G) is a whole-
blood test for use as an aid in diagnosing
Mycobacterium tuberculosis infection, including latent
tuberculosis infection (LTBI) and tuberculosis (TB)
disease. This test was approved by the U.S. Food and
Drug Administration (FDA) in 2005.
QFT
 A positive result suggests that M. tuberculosis
infection is likely; a negative result suggests that
infection is unlikely
Positive Test Results
 You will see the provider at Student Health
 Sent to the hospital to have a Chest x-ray
 You will then come back to Student Health for results
and evaluation.
Treatment Options
 Active TB cases will be sent to an infectious disease
physician to manage
 Latent TB cases (the majority):
 Take the treatment


Rifampin daily treatment for 4 months. You will have blood
taken before treatment and the 1st, 2nd, and 3rd month of
treatment
You will come into student health for monthly visits to
identify signs or symptoms of adverse drug effects and for
medication refills.
Treatment Options
 You have to decide the risk and benefits of treatment
versus the latent infection becoming active.
 You may decide not to take treatment

If so, you will be asked to come in every 6 months and review
signs and symptoms of active disease at Student Health.
 You should be aware of your chances of getting active
tuberculosis
Adherence
 Important that once you start treatment that you
adhere to the medication regime.
 If we need to stop the treatment because of side effects
we will discuss options from there.
 Drug resistant Tuberculosis has been associated with
the incomplete treatment of Latent Tuberculosis.
We are here for you
 We want to keep you healthy and also keep the campus
community healthy.
 The goal is to keep you in class so that you are able to
complete your degree and move on to your
professional life.
 It is important that you review this information and
then we can answer questions as they arise.
References
• Center for Disease Control and Prevention, Tuberculosis,
http://www.cdc.gov/tb/
 ACHA guidelines: Tuberculosis screening and targeted
testing of college and university students (2012).
http://www.acha.org/Publications/docs/ACHA_Tubercu
losis_Screening_Apr2012.pdf