Transcript Slide 1

CanLift
Resistance Training Exercise Program for
Post Treatment Cancer Survivors
Miss Danielle Girard
Chief Investigator
Dr Jack Cannon & Dr Stephen Bird
Research Supervisors
Presentation Overview
Introduction to the CanLift Exercise Program
Benefits of Exercise for Cancer Survivors
Post Cancer Fatigue (PCF)
Overview of the CanLift Training Program
Participant Selection Criteria
Contact Details
CanLift Training Program
 Accredited Exercise Physiologists in the School of Human
Movement Studies at Charles Sturt University as part of a PhD
research project have developed a unique exercise program
CanLift designed to serve post-treatment cancer survivors.
The purpose of CanLift is to provide post-treatment cancer
survivors in the Bathurst Community the opportunity to partake in
an individualized prescriptive resistance training exercise program
designed to assist in the management of cancer treatment-related
symptoms.
The exercise program will be offered free of charge and will start in
September, 2012 and will run for a period of eight weeks.
Post Cancer Fatigue
 Persistent fatigue is a distressing symptom frequently experienced
by disease-free post-treatment cancer survivors, which impacts
negatively upon physical functioning and quality of life.
As such, clinicians and health care providers are increasingly
recognising that Post Cancer Fatigue (PCF) is a significant health
problem that warrants intervention.
The mechanisms associated with PCF are still under investigation;
however, strong evidence exist suggesting that exercise is a
beneficial treatment modality for managing PCF symptoms.
Exercise Related Health Benefits
 Exercise is considered safe following most types of
cancer treatment.
Research has shown that exercise can:
Reduce cancer and treatments related side-effects
such as fatigue symptoms
Increased health related quality of life in diseasefree post-treatment cancer survivors and
Reduce the risk of cancer recurring in some
disease-free post-treatment cancer survivors
Exercise Related Health Benefits
Previous studies have focused on the benefits of aerobic
and/or mixed aerobic and resistance training modalities; few
studies have exclusively examined the benefits of resistance
based exercise on fatigue symptoms and health related quality
of life.
Knowledge of whether resistance training exercise alone can
improve fatigue symptoms in this population is currently
limited. However, as post-cancer fatigue appears to be related
to changes in motor drive and central
nervous system function, it is
reasonable to suggest that resistance
training will help to reduce fatigue
symptoms.
Exercise Related Health Benefits
Resistance Training (RT) in healthy populations
has been shown to improve; lean body mass,
muscle protein mass and contractile force, selfesteem, physical fitness and quality of life. RT
influences metabolic and hormonal responses and
elicits architectural and neural adaptations.
Skeletal muscle has been shown to be highly
adaptable even in the presence of sever muscle
loss and fatigue, provided an appropriate training
stimuli is applied.
Based on this logic, it is hypothesised that an 8
week resistance training intervention will positively
affect muscular strength, fatigue, functional status
and quality of life in persons with PCF.
Aim Of The CanLift Training Program
Understanding if and how resistance training works to
mitigate fatigue symptoms will assist in the development
of exercise based strategies aimed at reducing symptoms
in disease-free post treatment cancer survivors.
Hence, the aim of this research project is to:
Examine the effect of resistance training on
the symptoms of PCF in disease-free posttreatment cancer survivors with PCF and the
neuromuscular adaptations to resistance
training.
The CanLift Training Program
CanLift Training Program
STUDY PARTICIPANTS
Research participants include:
1) Disease-free, post treatment cancer survivors with
Post Cancer Fatigue (PCF) with various cancer
diagnoses (e.g. prostate, colon, testicular, ovarian etc
with the exception of lung and brain cancer types)
2) Healthy post-cancer survivors
without PCF
CanLift Training Program
PARTICIPANTS REQUIREMENTS
Healthy persons will be matched to the cancer survivor based on:
Age
Height
Body Composition
Sleeping Patterns And
Habitual Physical Activity Levels
 All subjects will be
Aged Between 40-70 Years
Non-smokers
Participants must have no current musculoskeletal, metabolic, or
cardiovascular conditions that may influence the results obtained in this
study.
Cancer survivors will be disease-free and have ceased receiving cancer
related treatments for a minimum period of 6 months.
CanLift Training Program
RESEARCH GROUPS
Participants will be randomised into four groups:
Two Resistance Training Groups
1) Disease-free, post-treatment cancer participants with PCF who will
participate in a 8 week resistance training program
2) Healthy post-cancer survivors without PCF who will participate in a 8
week resistance training program
Two Control Condition Groups
1) Disease-free, post-treatment cancer participants with PCF who will not
participate in a 8 week resistance training program
2) Healthy post-cancer survivors without PCF who will participate in a 8
week resistance training program
CanLift Training Program
CONTROL CONDITION
Participants not undertaking the resistance training program will be
instructed to not undertake any structured exercise training, continue
their normal physical activities and nutrition patterns for the duration
of the 8 week intervention period.
Participants will be provided with dietary and physical activity
journals to document dietary and physical activities over the 8 week
period.
Following the completion of data collection, participants in the
control group will be invited to commence an individually tailored
resistance exercise training program at CSU.
Following data collection, participants in the control group will be
invited to complete the resistance exercise training program
CanLift Training Program
RESISTANCE TRAINING GROUPS
The exercise program consists of structured resistance training
sessions performed twice weekly.
A minimum of one (1) day rest will be provided between exercise
sessions
The training intensity will be between 50-80% 1RM depending on
pre-session fatigue questionnaire responses. Intensity will be reduced
on days of heightened fatigue symptoms.
Each session will consist of a Warm-up, Conditioning and Cooldown
Session duration will be approximately 1 hours in duration
Sessions will be conducted at Charles Sturt University, Bathurst campus in
the Exercise Physiology and Functional Rehabilitation Clinic, building E1
CanLift Training Program
Resistance Training Exercise Protocol
Exercise
Repetitions
Sets
Tempo
Rest
Intensity
(% 1RM)
Leg Press
8 - 12
3
2:1:2
2 min
50-80%
Leg Extension
8 - 12
3
2:1:2
2 min
50-80%
Cable Squat
8 - 12
3
2:1:2
2 min
50-80%
Lat Pulldown
8 - 12
3
2:1:2
2 min
50-80%
Chest Press
8 - 12
3
2:1:2
2 min
50-80%
Shoulder Press
8- 12
3
2:1:2
2 min
50-80%
Exercises to be performed during each resistance training session
Participant Benefits
 Several meaningful health related benefits can be gained by
participants, including:
Comprehensive health screening appraisal, providing information regarding
risk of developing secondary health conditions (e.g. Heart disease, diabetes,
obesity, etc)
Opportunity to participate in a fully supervised resistance based exercise
intervention.
Exercise has demonstrated to be an effective non-pharmacological
management strategy for reducing fatigue symptoms; thus an improvement
in fatigue symptoms in persons with PCF can be anticipated.
Other potential health related benefits reported with participation in
resistance training programs include increased bone mineral density and fat
free mass, reduced fat mass and increased muscular strength.
We invite you to participate in this exciting research project
Study Benefits
The primary benefit to Charles Sturt University is the
collection of data for a PhD project, conducted by Ms
Danielle Girard entitled:
A Comparison Of The Physiological, Neuromuscular,
Perceptual And Performance Adaptations During
Different Exercise Fatigue Tasks And Following 12
weeks Between Disease-Free Breast Cancer Survivors
With Post Cancer Fatigue And Healthy Matched
Persons
Contact Details
If you are interested in participating in this exercise program or
would like more information please contact:
Miss Danielle Girard Dip Fitness, B. Ex Sci (Hons), ESSAM, AEP
School of Human Movement Studies
Panorama Av, Bathurst NSW 2795
Tel: 02 63 38 6101
Email: [email protected]
Reference List
ACSM’s Exercise management for people with chronic diseases and disabilities
(3rd ed.)
Al-Majid, S., & Gray, D. P. (2009). A biobehavioral model for the study of exercise
interventions in cancer-related fatigue. Biological Research for Nursing, 10(4), 381.
Ardies, C. M. (2002). Exercise, cachexia, and cancer therapy: a molecular
rationale. Nutrition and cancer, 42(2), 143-157.
Courneya, K. S., Friedenreich, C. M., Sela, R. A., Quinney, H. A., Rhodes, R. E., &
Jones, L. W. (2004). Exercise motivation and adherence in cancer survivors after
participation in a randomized controlled trial: an attribution theory perspective.
International journal of behavioral
Courneya, K., Mackey, J., & McKenzie, D. (2002). Exercise for breast cancer
survivors. The Physician and Sports Medicine, 30 (8), 33, 42.
Reference List
Courneya, K., Segal, R., Mackey, J., Gelmon, K., Ried, R., Freidenreich, C., Ladha,
A., Proulx, C., Vallance, K., Yutaka, Y. & McKenzie, D. (2007). Effects of aerobic and
resistance exercise in breast cancer patients receiving adjuvant chemotherapy: A
multicentre randomized control trial. Journal of Clinical Oncology 25(28): 4396-4403.
De Backer, I., G. Schep, et al. (2009). Resistance training in cancer survivors: a
systematic review. Int J Sports Med 30(10): 703-712.
De Backer, IC, Vreugdenhil, G.,Nijziel, MR, Kesta, AD., van Breda, E. &Schep, G.
(2008). Long-term follow-up after cancer rehabilitation using high-intensity
resistance training: persistent improvement of physical performance and quality of
life. British Journal of Cancer 99:30-36
Kangas, M., D. H. Bovbjerg, et al. (2008). Cancer-related fatigue: A systematic and
meta-analytic review of non-pharmacological therapies for cancer patients.
Psychological Bulletin 134(5): 700.
Peterson, M., Pistilli, E., Haff, G., Hoffman, E. & Gordon, P. (2011). Progression of
volume load and muscular adaptation during resistance exercise. European Journal
of Applied Physiology, 111:1063-1071.