Transcript Affects

Genetic Disorders and Birth
Defects
Cleft lip/pallet
Affects: anyone, more common in asians and
native americans
When appears: birth
Method of inheritance: mulifactoral
Effect on person: two sides of lip and/or pallet
not joined
Treatment: surgery
Clubfoot
Affects: Anyone
When appears: Birth
Method of inheritance: Multifactoral
Effect on person: Foot and ankle twisted,
making it impossible to walk normally
Treatment: surgery, corrective shoes
Color Blindness
Affects: Males
When appears: Birth
Method of inheritance: x-linked
Effect on person: Inability to distinguish certain
colors
Treatment: none- just help adapt
Cystic Fibrosis
Affects: Anyone
When appears: Birth, some in adult-hood
Method of inheritance: Recessive
Effect on person: Lack of an enzyme, mucous
obstructions in body, especially in lungs and
digestion; growth retardation
Treatment: respiratory help
Diabetes
Affects: Anyone
When appears: Birth or later
Method of inheritance: Multifactoral
Effect on person: Abnormal metabolism of
sugar because body doesn’t produce enough
insulin
Treatment: insulin shots/ oral diet
Down’s Syndrome
Affects: Anyone, more common to young or old
parents
When appears: Birth
Method of inheritance: Chromosomal error
Effect on person: Some form of mental retardation;
oval shaped eyes; thick, big tongue; short neck;
back of head is flat; ears small; nose flat and wide;
shorter, loose joints; heart problems
Treatment: therapy; special assistance
Hemophilia
Affects: Males
When appears: Birth
Method of inheritance: x-linked
Effect on person: absence of clotting factor in
blood, crippling and death from internal
bleeding
Treatment: transfussions
Huntington’s Disease
Affects: Parents must have
When appears: Middle ages
Method of inheritance: Dominant
Effect on person: Deterioration of body and
brain in middle age; death
Treatment: none
Hydrocephalus
Affects: Anyone
When appears: Birth
Method of inheritance: Multifactoral
Effect on person: Obstruction causes water on
brain; produce brain damage and death
Treatment: surgery, put in shunt
Marfan’s Syndrome
Affects: Parent must carry
When appears: Birth
Method of inheritance: Dominant
Effect on person: Heart Malformation, hearing
loss, eye weakness
Treatment: surgery, antibiotics, physical therapy,
regular checkups
Muscular Dystrophy
Affects: Anyone
When appears: childhood, adulthood
Method of inheritance: Multifactoral
Effect on person: weakening of muscles,
inability to walk or move
Treatment: none
Phenylketonuria (PKU)
Affects: Anyone
When appears: Birth
Method of inheritance: Recessive
Effect on person: Abnormal digestion of
protein; hyperactivity
Treatment: preventable diet
Polydactyl
Affects: Parent carry
When appears: Birth
Method of inheritance: Dominant
Effect on person: Extra fingers and toes
Treatment: surgery
Sickle Cell Anemia
Affects: Anyone
When appears: Birth
Method of inheritance: Recessive
Effect on person: Abnormal blood cells; bouts
of pain, heart and kidney failure, less oxygen
Treatment: transfusions
Spina Bifida
Affects: Anyone
When appears: Birth
Method of inheritance: Multifactoral
Effect on person: Varies from slight cyst to open
spine
Treatment: surgery, physical therapy
Tay-Sachs
Affects: Anyone
When appears: 6 months,
Method of inheritance: MultiRecessive
Effect on person: Enzyme disease causing
inability to break down fatty deposits in brain
and nerve cells; cells clog and shut down
nervous system; apparently healthy at birth,
death by age 3
Treatment: none
Thalassemia
Affects: Anyone
When appears: Birth
Method of inheritance: Recessive
Effect on person: Abnormal blood cells;
paleness and listlessness, low resistance to
infection; do no produce enough red blood cells;
liver and spleen enlarged
Treatment: blood transfusions