Transcript Hh - Cloudfront.net

Genetics Game
Autosomal Recessive Inheritance
Autosomal Dominant Inheritance
Sex-Linked Inheritance
1)Which choice(s) are examples of
homozygous recessive genotypes?
1. TT
6. XY
2. Tall
7. gg
3. Hh
8. Dwarf
4. pp
9. yY
5. Wrinkled
10. hh
2) Name 3 out of 7 traits of pea
plants Gregor Mendel studied?
3) What is the genotype of the
child, assuming autosomal
recessiveness?
4) What do you call a gene that is
hidden?
5) Using below Punnett Square results,
what is the chance a child would be
born healthy (autosomal dominant
disorder)?
H
h
H
HH
Hh
h
Hh
hh
6) What are chromosomes 1-22
referred as?
7) Two part question:
a)
Are men or women more likely to inherit sexlinked disorders
b)
who do they usually inherit the disorder from?
8) Steve is a normal pigmented man with
no history of albinism in his family, and he
marries Anne, an albino woman. Albinism
is an autosomal recessive disorder. Steve
and Anne have a child. What is the
probability that child will be an albino?
(Hint: Draw a Punnett Square if it would help.)
9) Three part question:
a)
What does a shape with a dot in the middle
signify?
b)
What is the genotype of this person assuming
autosomal recessive inheritance?
c)
What is the genotype of this person assuming
sex-linked inheritance?
10) Harry is color blind, which is a sexlinked disorder. He married Ginny who is
not color blind but whose father was color
blind. What is the probability their first
born son will be color blind?
(Hint: Use a Punnett Square or pedigree to help
figure out.)
11) Alternative versions of genes
are called?
12) If you flip a coin:
a. What is the probability of
getting heads?
b. What is the probability of getting
HEADS four times in a row?
13) Aicardi Syndrome is a dominant disorder
found on the X chromosome of males and
females. Michelle is heterozygous for Aicardi
syndrome, but her husband Jerry is completely
healthy. List the genotypes in the F1
generation. (Use a Punnett Square.)
14) Selena is a carrier of PKU. Her parents were
also both carriers of this recessive disorder. She
marries Justin, who is heterozgyous for PKU.
They have three kids, two boys and a girl. Their
daughter has been showing signs of PKU. Draw a
pedigree of their family, including genotypes.
2 Unknowns
15) Fill in the missing genotype
and explain how you know.
16) Write out the two types of
genotypes a male can have when
referring to sex-linked disorders.
(Use the letter H.)
17) What is the genotype of the
child, assuming sex-linked
inheritance?
18) Where was Gregor Mendel
from and what was his profession?
19) Huntington’s Disease is an autosomal
dominant disorder. Kelly had Huntington’s
disease and before she died at the age of 38, she
married and had 2 kids. Her husband, Fred, was
completely healthy. What are the chances that
both her children will be born with Huntington’s
disease?
(Hint: Use a Punnett Square if needed to solve.)
20) Grab-Bag: Name 5 songs of
Michael Jackson.
Exchange answers
and correct
.
1)Which choice(s) are examples of
homozygous recessive genotypes?
4, 7, 10
1. TT
6. XY
2. Tall
7. gg
3. Hh
8. Dwarf
4. pp
9. yY
5. Wrinkled
10. hh
2) Name 3 out of 7 traits of pea
plants Gregor Mendel studied?
Seed Texture
Seed Color
Pod Shape
FlowerPosition
Stem Height
Pod Color
Flower Color
3) What is the genotype of the
child?
hh
4) What do you call a gene that is
hidden? RECESSIVE
5) Using below Punnett Square results,
what is the chance a child would be
born healthy (autosomal dominant
disorder)?
H
h
H
HH
Hh
h
Hh
hh
¼ or
25%
6) What are chromosomes 1-22
referred as? AUTOSOMES
7) Two part question:
a)
Are men or women more likely to inherit sexlinked disorders
Men
b)
who do they usually inherit the disorder from?
Mother
8) Steve is a normal pigmented man with
no history of albinism in his family, and he
marries Anne, an albino woman. Albinism
is an autosomal recessive disorder. Steve
and Anne have a child. What is the
probability that child will be an albino?
0%
(Hint: Draw a Punnett Square if it would help.)
9) Three part question:
a)
What does a shape with a dot in the middle
signify? Person is a carrier.
b)
What is the genotype of this person assuming
autosomal recessive inheritance? Hh
c)
What is the genotype of this person assuming
sex-linked inheritance?
XH Xh
10) Harry is color blind, which is a sexlinked disorder. He married Ginny who is
not color blind but whose father was color
blind. What is the probability their first
born son will be color blind?
(Hint: Use a Punnett Square or pedigree to help
figure out.)
½ or
50%
11) Alternative versions of genes
are called?
ALLELES
12) If you flip a coin:
a. What is the probability of
getting heads?
50% or ½
b. What is the probability of getting
HEADS four times in a row?
1/16
13) Aicardi Syndrome is a dominant disorder
found on the X chromosome of males and
females. Michelle is heterozygous for Aicardi
syndrome, but her husband Jerry is completely
healthy. List the genotypes in the F1
generation. (Use a Punnett Square.)
H
h
X X
h
h
XX
H
X Y
h
XY
14) Selena is a carrier of PKU. Her parents were
also both carriers of this recessive disorder. She
marries Justin, who is heterozgyous for PKU.
They have three kids, two boys and a girl. Their
daughter has been showing signs of PKU. Draw a
pedigree of their family, including genotypes.
2 Unknowns
15) Fill in the missing genotype
and explain how you know.
Hh, because in
order for parents
to have kid with
disease, both must
have a little h, and
mom must also
have big H since
she is healthy.
16) Write out the two types of
genotypes a male can have when
referring to sex-linked disorders.
(Use the letter H.)
H
X Y
h
XY
17) What is the genotype of the
child, assuming sex-linked
inheritance?
h
X
Y
18) Where was Gregor Mendel
from and what was his profession?
AUSTRIA
MONK
19) Huntington’s Disease is an autosomal
dominant disorder. Kelly had Huntington’s
disease and before she died at the age of 38, she
married and had 2 kids. Her husband, Fred, was
completely healthy. What are the chances that
both her children will be born with Huntington’s
disease? (Hint: Use a Punnett Square if needed to solve.)
¼ or 25%
20) Grab-Bag: Name 5 songs of
Michael Jackson. Thriller
Bad
Beat It
Billie Jean
Black and White
Dirty Diana
PYT
Remember the Time
Rock With You
Man in the Mirror
Smooth Criminal
Jam
Scream
Wanna Be Startin’ Something
Human Nature
Working Day & Night