Transcript ch 16 clicker questions

CLICKER QUESTIONS
For CAMPBELL BIOLOGY, NINTH EDITION
Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Chapter 16
The Chromosomal Basis of
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Inheritance
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Questions prepared by
Louise Paquin
McDaniel College
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Who conducted the X-ray diffraction studies
that were key to the discovery of the structure
of DNA?
a) Griffith
b) Franklin
c) Meselson and Stahl
d) Chargaff
e) McClintock
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How do the leading and the lagging strands differ?
a) The leading strand is synthesized in the same direction
as the movement of the replication fork, and the lagging
strand is synthesized in the opposite direction.
b) The leading strand is synthesized at twice the rate of the
lagging strand.
c) The lagging strand is synthesized continuously, whereas
the leading strand is synthesized in short fragments that
are ultimately stitched together.
d) The leading strand is synthesized by adding nucleotides
to the 3' end of the growing strand, and the lagging strand
is synthesized by adding nucleotides to the 5' end.
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The DNA Model
What kind of evidence about the structure of
DNA came from each of the following branches
of science?
a) physics
b) chemistry
c) biology
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The Genetic Material
If the result of the Hershey and Chase
experiment had been that radioactive sulfur
(35S) was found inside the cells instead of
radioactive phosphorous (32P), what could
have been concluded?
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Semiconservative Replication
Define and diagram “semiconservative” as it
applies to DNA replication.
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Replication
If a segment of DNA (circular or linear) is able
to replicate, it must include which of the
following?
a) two double helices
b) at least one origin of replication
c) at least 3 million nucleotide pairs
d) two or more mutated regions
e) a binding site for ligase
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Replication Enzymes
In what order do the following enzymes and
polypeptides function during replication?
a) single-strand binding proteins
b) DNA polymerase III
c) helicase
d) primase
e) topoisomerase
f) ligase
g) DNA polymerase I
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Replication
Where and how is a
new nucleotide added
to the DNA strand
during replication?
What enzyme is
needed?
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Telomeres
Telomeres, or the ends of linear chromosomes,
have special structure and function, even though
they are non-coding. Describe their structure and
function.
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Shortened Ends
What enzyme does a gamete-producing cell
include that compensates for replicationassociated shortening?
a) DNA polymerase II
b) ligase
c) telomerase
d) DNA nuclease
e) proofreading enzyme
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Packaging
Arrange the following in order of size, from
smallest to largest.
a) scaffolded domains
b) double helix
c) metaphase chromosome
d) nucleosome
e) 30 nm fiber
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Heterochromatin
Which of the following is true of
heterochromatin but not of euchromatin?
a) It is accessible to enzymes needed for gene
expression.
b) It becomes less tightly compacted after cell division.
c) It includes DNA primarily found in expressed genes.
d) It appears more pale when observed
microscopically.
e) It remains tightly coiled at the G1 phase.
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